Is oxytocin “nature's medicine”?

CS Carter, WM Kenkel, EL MacLean, SR Wilson… - Pharmacological …, 2020 - ASPET
Oxytocin is a pleiotropic, peptide hormone with broad implications for general health,
adaptation, development, reproduction, and social behavior. Endogenous oxytocin and …

[HTML][HTML] The role of oxytocin and the effect of stress during childbirth: neurobiological basics and implications for mother and child

MH Walter, H Abele, CF Plappert - Frontiers in endocrinology, 2021 - frontiersin.org
The neuropeptide oxytocin acts as a hormone and a neuromodulator, influencing a
multitude of human social behaviors, including reproduction. During childbirth and the …

Oxytocin administration in neonates shapes hippocampal circuitry and restores social behavior in a mouse model of autism

A Bertoni, F Schaller, R Tyzio, S Gaillard, F Santini… - Molecular …, 2021 - nature.com
Oxytocin is an important regulator of the social brain. In some animal models of autism,
notably in Magel2 tm1. 1Mus-deficient mice, peripheral administration of oxytocin in infancy …

Maternal and newborn plasma oxytocin levels in response to maternal synthetic oxytocin administration during labour, birth and postpartum–a systematic review with …

S Buckley, K Uvnäs-Moberg, Z Pajalic… - BMC pregnancy and …, 2023 - Springer
Background The reproductive hormone oxytocin facilitates labour, birth and postpartum
adaptations for women and newborns. Synthetic oxytocin is commonly given to induce or …

Genetic, epigenetic, and environmental factors controlling oxytocin receptor gene expression

JS Danoff, KL Wroblewski, AJ Graves, GC Quinn… - Clinical …, 2021 - Springer
Background The neuropeptide oxytocin regulates mammalian social behavior. Disruptions
in oxytocin signaling are a feature of many psychopathologies. One commonly studied …

Sex, love and oxytocin: Two metaphors and a molecule

CS Carter - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Dozens of studies, most conducted in the last four decades, have implicated oxytocin, as
well as vasopressin and their receptors, in processes that mediate selective sociality and the …

[HTML][HTML] Oxytocin and love: myths, metaphors and mysteries

CS Carter - Comprehensive Psychoneuroendocrinology, 2022 - Elsevier
Oxytocin is a peptide molecule with a multitude of physiological and behavioral functions.
Based on its association with reproduction-including social bonding, sexual behavior, birth …

Oxytocin: at birth and beyond. A systematic review of the long‐term effects of peripartum oxytocin

DT Monks, A Palanisamy - Anaesthesia, 2021 - Wiley Online Library
Oxytocin is one of the most commonly used medications during labour and delivery. Recent
insights from basic neuroscience research suggest that the uterotonic effects of oxytocin may …

The oxytocin system and early‐life experience‐dependent plastic changes

T Onaka, Y Takayanagi - Journal of Neuroendocrinology, 2021 - Wiley Online Library
Early‐life experience influences social and emotional behaviour in adulthood. Affiliative
tactile stimuli in early life facilitate the development of social and emotional behaviour …

Oxytocin receptor DNA methylation is associated with exogenous oxytocin needs during parturition and postpartum hemorrhage

EN Erickson, L Myatt, JS Danoff, KM Krol… - Communications …, 2023 - nature.com
Background The oxytocin receptor gene (OXTR) is regulated, in part, by DNA methylation.
This mechanism has implications for uterine contractility during labor and for prevention or …