Traditional and novel electrocardiographic conduction and repolarization markers of sudden cardiac death

G Tse, BP Yan - Europace, 2017 - academic.oup.com
Sudden cardiac death, frequently due to ventricular arrhythmias, is a significant problem
globally. Most affected individuals do not arrive at hospital in time for medical treatment …

[HTML][HTML] Brugada syndrome: A comprehensive review of pathophysiological mechanisms and risk stratification strategies

KHC Li, S Lee, C Yin, T Liu, T Ngarmukos, G Conte… - IJC Heart & …, 2020 - Elsevier
Brugada syndrome (BrS) is an inherited ion channel channelopathy predisposing to
ventricular arrhythmias and sudden cardiac death. Originally believed to be predominantly …

[HTML][HTML] Electrophysiological mechanisms of long and short QT syndromes

G Tse, YWF Chan, W Keung, BP Yan - IJC Heart & Vasculature, 2017 - Elsevier
The QT interval on the human electrocardiogram is normally in the order of 450 ms, and
reflects the summated durations of action potential (AP) depolarization and repolarization of …

The mechanical uncoupler blebbistatin is associated with significant electrophysiological effects in the isolated rabbit heart

KE Brack, R Narang, J Winter… - Experimental physiology, 2013 - Wiley Online Library
New Findings• What is the central question of this study? Does the mechanical uncoupler
blebbistatin affect cardiac electrophysiology?• What is the main finding and what is its …

Incorporating latent variables using nonnegative matrix factorization improves risk stratification in Brugada syndrome

G Tse, J Zhou, S Lee, T Liu, G Bazoukis… - Journal of the …, 2020 - Am Heart Assoc
Background A combination of clinical and electrocardiographic risk factors is used for risk
stratification in Brugada syndrome. In this study, we tested the hypothesis that the …

T‐wave morphology restitution predicts sudden cardiac death in patients with chronic heart failure

J Ramírez, M Orini, A Mincholé… - Journal of the …, 2017 - Am Heart Assoc
Background Patients with chronic heart failure are at high risk of sudden cardiac death
(SCD). Increased dispersion of repolarization restitution has been associated with SCD, and …

New approach for T-wave peak detection and T-wave end location in 12-lead paced ECG signals based on a mathematical model

JPV Madeiro, WB Nicolson, PC Cortez… - Medical engineering & …, 2013 - Elsevier
This paper presents an innovative approach for T-wave peak detection and subsequent T-
wave end location in 12-lead paced ECG signals based on a mathematical model of a …

[HTML][HTML] Predictive Value of Tpeak – Tend Indices for Adverse Outcomes in Acquired QT Prolongation: A Meta-Analysis

G Tse, M Gong, L Meng, CW Wong, G Bazoukis… - Frontiers in …, 2018 - frontiersin.org
Background: Acquired QT interval prolongation has been linked with malignant ventricular
arrhythmias, such as torsade de pointes, in turn predisposing to sudden cardiac death …

Peri-infarct quantification by cardiac magnetic resonance to predict outcomes in ischemic cardiomyopathy: prognostic systematic review and meta-analysis

H Haghbayan, N Lougheed, DP Deva… - Circulation …, 2019 - Am Heart Assoc
Background: In ischemic cardiomyopathy, cardiac magnetic resonance assessment of the
peri-infarct zone, a potential substrate for arrhythmogenesis, may serve as a novel …

Docosahexaenoic acid, but not eicosapentaenoic acid, supplementation reduces vulnerability to atrial fibrillation

A Ramadeen, KA Connelly, H Leong-Poi… - Circulation …, 2012 - Am Heart Assoc
Background—The potential health benefits of ω-3 polyunsaturated fatty acids (PUFAs)
usually are studied using a combination of docosahexaenoic acid (DHA) and …