Extensive research within the last several decades has revealed that the major risk factors
for most chronic diseases are infections, obesity, alcohol, tobacco, radiation, environmental …

A growing awareness of the mechanisms by which phytochemicals can influence upstream
endogenous cellular defence processes has led to intensified research into their potential …

Although a high intake of plant foods such as fruits, vegetables, whole grains, nuts, and
legumes has been recommended for chronic disease prevention, it has been unclear what …

Epigenetic mechanisms control gene expression during normal development and their
aberrant regulation may lead to human diseases including cancer. Natural phytochemicals …

Chemoprevention—the use of medication to prevent cancer—can be augmented by the
consumption of produce enriched with natural metabolites. However, chemopreventive …

The complex role of NRF2 in the context of cancer continues to evolve. As a transcription
factor, NRF2 regulates various genes involved in redox homeostasis, protein degradation …

Cancer is the second deadliest disease worldwide. Although recent advances applying
precision treatments with targeted (molecular and immune) agents are promising, the …

Sulforaphane (SFN), a compound derived from cruciferous vegetables that has been shown
to be safe and nontoxic, with minimal/no side effects, has been extensively studied due to its …

In the last several years, numerous molecules derived from plants and vegetables have
been tested for their antioxidant, anti-inflammatory, and anti-aging properties. One of them is …

In the past decades, extensive studies have reported the potential chemopreventive activity
of sulforaphane, an isothiocyanate derived from glucoraphanin, occurring in large amounts …