Metabolic determinants of Alzheimer's disease: A focus on thermoregulation
M Tournissac, M Leclerc, J Valentin-Escalera… - Ageing Research …, 2021 - Elsevier
Alzheimer's disease (AD) is a complex age-related neurodegenerative disease, associated
with central and peripheral metabolic anomalies, such as impaired glucose utilization and …
with central and peripheral metabolic anomalies, such as impaired glucose utilization and …
[HTML][HTML] Obesity and brain function: The brain–body crosstalk
Dementia comprises a wide range of progressive and acquired neurocognitive disorders.
Obesity, defined as excessive body fat tissue, is a common health issue world-wide and a …
Obesity, defined as excessive body fat tissue, is a common health issue world-wide and a …
Relationship between adipokines, cognition, and brain structures in old age depending on obesity
Background Adipokines such as leptin and adiponectin are associated with cognitive
function. Although adiposity crucially affects adipokine levels, it remains unclear whether the …
function. Although adiposity crucially affects adipokine levels, it remains unclear whether the …
Adiponectin Attenuates Splenectomy-Induced Cognitive Deficits by Neuroinflammation and Oxidative Stress via TLR4/MyD88/NF-κb Signaling Pathway in Aged Rats
Z Zhang, L Guo, F Yang, S Peng, D Wang… - ACS Chemical …, 2023 - ACS Publications
Perioperative neurocognitive disorder (PND) is a common adverse event after surgical
trauma in elderly patients. The pathogenesis of PND is still unclear. Adiponectin (APN) is a …
trauma in elderly patients. The pathogenesis of PND is still unclear. Adiponectin (APN) is a …
[HTML][HTML] MicroRNA: a linking between astrocyte dysfunction, mild cognitive impairment, and neurodegenerative diseases
AE Ramírez, N Gil-Jaramillo, MA Tapias… - Life, 2022 - mdpi.com
Simple Summary Neurodegenerative diseases are complex neurological disorders with a
high incidence worldwide in older people, increasing hospital visits and requiring expensive …
high incidence worldwide in older people, increasing hospital visits and requiring expensive …
[HTML][HTML] Harnessing the power of Leptin: the biochemical link connecting obesity, diabetes, and cognitive decline
P Grasso - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
In this review, the current understanding of leptin's role in energy balance, glycemic
regulation, and cognitive function is examined, and its involvement in maintaining the …
regulation, and cognitive function is examined, and its involvement in maintaining the …
Associations of Serum Insulin and Related Measures With Neuropathology and Cognition in Older Persons With and Without Diabetes
Z Arvanitakis, AW Capuano, H Tong… - Annals of …, 2024 - Wiley Online Library
Objective To examine associations of serum insulin and related measures with
neuropathology and cognition in older persons. Methods We studied 192 older persons (96 …
neuropathology and cognition in older persons. Methods We studied 192 older persons (96 …
[HTML][HTML] Pharmacological and physiological roles of adipokines and myokines in metabolic-related dementia
A Arjunan, J Song - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Dementia is a detrimental neuropathologic condition with considerable physical, mental,
social, and financial impact on patients and society. Patients with metabolic syndrome …
social, and financial impact on patients and society. Patients with metabolic syndrome …
Cancer‐related fatigue: Towards a more targeted approach based on classification by biomarkers and psychological factors
ME Schmidt, T Maurer, S Behrens… - … journal of cancer, 2024 - Wiley Online Library
Cancer‐related fatigue is a frequent, burdensome and often insufficiently treated symptom. A
more targeted treatment of fatigue is urgently needed. Therefore, we examined biomarkers …
more targeted treatment of fatigue is urgently needed. Therefore, we examined biomarkers …
An exploratory research report on brain mineralization in postoperative delirium and cognitive decline
F Lammers‐Lietz, F Borchers, I Feinkohl… - European Journal of …, 2024 - Wiley Online Library
Delirium is a severe postoperative complication associated with poor overall and especially
neurocognitive prognosis. Altered brain mineralization is found in neurodegenerative …
neurocognitive prognosis. Altered brain mineralization is found in neurodegenerative …