A survey of best practices for RNA-seq data analysis
Abstract RNA-sequencing (RNA-seq) has a wide variety of applications, but no single
analysis pipeline can be used in all cases. We review all of the major steps in RNA-seq data …
analysis pipeline can be used in all cases. We review all of the major steps in RNA-seq data …
MicroRNAs and complex diseases: from experimental results to computational models
Plenty of microRNAs (miRNAs) were discovered at a rapid pace in plants, green algae,
viruses and animals. As one of the most important components in the cell, miRNAs play a …
viruses and animals. As one of the most important components in the cell, miRNAs play a …
Identification of EMT signaling cross-talk and gene regulatory networks by single-cell RNA sequencing
AP Deshmukh, SV Vasaikar… - Proceedings of the …, 2021 - National Acad Sciences
The epithelial-to-mesenchymal transition (EMT) plays a critical role during normal
development and in cancer progression. EMT is induced by various signaling pathways …
development and in cancer progression. EMT is induced by various signaling pathways …
[HTML][HTML] Proteogenomic characterization of endometrial carcinoma
We undertook a comprehensive proteogenomic characterization of 95 prospectively
collected endometrial carcinomas, comprising 83 endometrioid and 12 serous tumors. This …
collected endometrial carcinomas, comprising 83 endometrioid and 12 serous tumors. This …
M2 macrophage-derived exosomes promote cell migration and invasion in colon cancer
J Lan, LI Sun, F Xu, L Liu, F Hu, D Song, Z Hou, W Wu… - Cancer research, 2019 - AACR
Clinical and experimental evidence has shown that tumor-associated macrophages promote
cancer initiation and progression. However, the macrophage-derived molecular …
cancer initiation and progression. However, the macrophage-derived molecular …
Circular RNA ciRS-7—a promising prognostic biomarker and a potential therapeutic target in colorectal cancer
W Weng, Q Wei, S Toden, K Yoshida, T Nagasaka… - Clinical Cancer …, 2017 - AACR
Purpose: Colorectal cancer is one of the most common malignancies worldwide. Recently, a
novel circular RNA, ciRS-7, was proposed to be a potential miR-7 sponge. As miR-7, a …
novel circular RNA, ciRS-7, was proposed to be a potential miR-7 sponge. As miR-7, a …
PDL1 Regulation by p53 via miR-34
Background: Although clinical studies have shown promise for targeting PD1/PDL1
signaling in non–small cell lung cancer (NSCLC), the regulation of PDL1 expression is …
signaling in non–small cell lung cancer (NSCLC), the regulation of PDL1 expression is …
miRWalk2. 0: a comprehensive atlas of microRNA-target interactions
H Dweep, N Gretz - Nature methods, 2015 - nature.com
miRWalk2. 0 (http://zmf. umm. uni-heidelberg. de/mirwalk2) is a comprehensive archive,
supplying the largest available collection of predicted and experimentally verified microRNA …
supplying the largest available collection of predicted and experimentally verified microRNA …
MicroRNA silencing for cancer therapy targeted to the tumour microenvironment
MicroRNAs are short non-coding RNAs expressed in different tissue and cell types that
suppress the expression of target genes. As such, microRNAs are critical cogs in numerous …
suppress the expression of target genes. As such, microRNAs are critical cogs in numerous …
WikiPathways: capturing the full diversity of pathway knowledge
Abstract WikiPathways (http://www. wikipathways. org) is an open, collaborative platform for
capturing and disseminating models of biological pathways for data visualization and …
capturing and disseminating models of biological pathways for data visualization and …