The passenger strand, miR-21-3p, plays a role in mediating cisplatin resistance in ovarian cancer cells
Objective Ovarian cancer is the deadliest gynaecological cancer. A major contributor to the
poor survival rate is the development of chemoresistance to platinum-based therapies such …
poor survival rate is the development of chemoresistance to platinum-based therapies such …
Therapeutic delivery of miR-200c enhances radiosensitivity in lung cancer
MA Cortez, D Valdecanas, X Zhang, Y Zhan… - Molecular Therapy, 2014 - cell.com
The microRNA (miR)-200s and their negative regulator ZEB1 have been extensively studied
in the context of the epithelial–mesenchymal transition. Loss of miR-200s has been shown …
in the context of the epithelial–mesenchymal transition. Loss of miR-200s has been shown …
Differential expression of microRNAs in adipose tissue after long-term high-fat diet-induced obesity in mice
Obesity is a major health concern worldwide which is associated with increased risk of
chronic diseases such as metabolic syndrome, cardiovascular disease and cancer. The …
chronic diseases such as metabolic syndrome, cardiovascular disease and cancer. The …
miEAA: microRNA enrichment analysis and annotation
Similar to the development of gene set enrichment and gene regulatory network analysis
tools over a decade ago, microRNA enrichment tools are currently gaining importance …
tools over a decade ago, microRNA enrichment tools are currently gaining importance …
[HTML][HTML] LIN28A is a suppressor of ER-associated translation in embryonic stem cells
LIN28 plays a critical role in developmental transition, glucose metabolism, and
tumorigenesis. At the molecular level, LIN28 is known to repress maturation of let-7 …
tumorigenesis. At the molecular level, LIN28 is known to repress maturation of let-7 …
A fast PC algorithm for high dimensional causal discovery with multi-core PCs
Discovering causal relationships from observational data is a crucial problem and it has
applications in many research areas. The PC algorithm is the state-of-the-art constraint …
applications in many research areas. The PC algorithm is the state-of-the-art constraint …
Principles of miRNA–mRNA interactions: beyond sequence complementarity
F Afonso-Grunz, S Müller - Cellular and Molecular Life Sciences, 2015 - Springer
MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally regulate gene
expression by altering the translation efficiency and/or stability of targeted mRNAs. In …
expression by altering the translation efficiency and/or stability of targeted mRNAs. In …
Protein-driven inference of miRNA–disease associations
S Mørk, S Pletscher-Frankild, A Palleja Caro… - …, 2014 - academic.oup.com
Motivation: MicroRNAs (miRNAs) are a highly abundant class of non-coding RNA genes
involved in cellular regulation and thus also diseases. Despite miRNAs being important …
involved in cellular regulation and thus also diseases. Despite miRNAs being important …
[HTML][HTML] Long non-coding RNA ZFAS1 interacts with CDK1 and is involved in p53-dependent cell cycle control and apoptosis in colorectal cancer
N Thorenoor, P Faltejskova-Vychytilova, S Hombach… - Oncotarget, 2016 - ncbi.nlm.nih.gov
We determined expression of 83 long non-coding RNAs (lncRNAs) and identified ZFAS1 to
be significantly up-regulated in colorectal cancer (CRC) tissue. In cohort of 119 CRC …
be significantly up-regulated in colorectal cancer (CRC) tissue. In cohort of 119 CRC …
MicroRNAs in renal cell carcinoma: diagnostic implications of serum miR-1233 levels
LM Wulfken, R Moritz, C Ohlmann, S Holdenrieder… - PloS one, 2011 - journals.plos.org
Background MicroRNA expression is altered in cancer cells, and microRNAs could serve as
diagnostic/prognostic biomarker for cancer patients. Our study was designed to analyze …
diagnostic/prognostic biomarker for cancer patients. Our study was designed to analyze …