Neutrophils in COVID-19

N Reusch, E De Domenico, L Bonaguro… - Frontiers in …, 2021 - frontiersin.org
Strong evidence has been accumulated since the beginning of the COVID-19 pandemic that
neutrophils play an important role in the pathophysiology, particularly in those with severe …

Hyperinflammation and derangement of renin-angiotensin-aldosterone system in COVID-19: a novel hypothesis for clinically suspected hypercoagulopathy and …

BM Henry, J Vikse, S Benoit, EJ Favaloro, G Lippi - Clinica chimica acta, 2020 - Elsevier
Early clinical evidence suggests that severe cases of coronavirus disease 2019 (COVID-19),
caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), are …

The versatile heparin in COVID‐19

J Thachil - Journal of Thrombosis and Haemostasis, 2020 - jthjournal.org
Coagulopathy in coronavirus infection has been shown to be associated with high mortality
with high D-dimers being a particularly important marker for the coagulopathy. 1 In the latest …

Arterial and venous thromboembolism in COVID-19: a study-level meta-analysis

BK Tan, S Mainbourg, A Friggeri, L Bertoletti… - Thorax, 2021 - thorax.bmj.com
Background The prevalence of venous thromboembolic event (VTE) and arterial
thromboembolic event (ATE) thromboembolic events in patients with COVID-19 remains …

NF-κB in monocytes and macrophages–an inflammatory master regulator in multitalented immune cells

M Mussbacher, M Derler, J Basílio… - Frontiers in …, 2023 - frontiersin.org
Nuclear factor κB (NF-κB) is a dimeric transcription factor constituted by two of five protein
family members. It plays an essential role in inflammation and immunity by regulating the …

Elevated troponin in patients with coronavirus disease 2019: possible mechanisms

G Tersalvi, M Vicenzi, D Calabretta, L Biasco… - Journal of cardiac …, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a pandemic that has affected more than
1.8 million people worldwide, overwhelmed health care systems owing to the high …

Neutrophils as regulators of cardiovascular inflammation

C Silvestre-Roig, Q Braster, A Ortega-Gomez… - Nature Reviews …, 2020 - nature.com
Neutrophils have traditionally been viewed as bystanders or biomarkers of cardiovascular
disease. However, studies in the past decade have demonstrated the important functions of …

[HTML][HTML] Devilishly radical NETwork in COVID-19: Oxidative stress, neutrophil extracellular traps (NETs), and T cell suppression

G Schönrich, MJ Raftery, Y Samstag - Advances in biological regulation, 2020 - Elsevier
Abstract Pandemic coronavirus disease 2019 (COVID-19) is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and poses an unprecedented challenge …

Cellular and molecular mechanisms of skin wound healing

OA Peña, P Martin - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Wound healing is a complex process that involves the coordinated actions of many different
tissues and cell lineages. It requires tight orchestration of cell migration, proliferation, matrix …

Cell type-specific roles of NF-κB linking inflammation and thrombosis

M Mussbacher, M Salzmann, C Brostjan… - Frontiers in …, 2019 - frontiersin.org
The transcription factor NF-κB is a central mediator of inflammation with multiple links to
thrombotic processes. In this review, we focus on the role of NF-κB signaling in cell types …