[HTML][HTML] A brief overview of global trends in MSC-based cell therapy

D Jovic, Y Yu, D Wang, K Wang, H Li, F Xu… - Stem cell reviews and …, 2022 - Springer
Human mesenchymal stem cells (MSCs), also known as mesenchymal stromal cells or
medicinal signaling cells, are important adult stem cells for regenerative medicine, largely …

Mesenchymal stem/stromal cell senescence: hallmarks, mechanisms, and combating strategies

Z Weng, Y Wang, T Ouchi, H Liu, X Qiao… - Stem Cells …, 2022 - academic.oup.com
Aging is a multifaceted and complicated process, manifested by a decline of normal
physiological functions across tissues and organs, leading to overt frailty, mortality, and …

Mesenchymal stem cells for neurological disorders

A Andrzejewska, S Dabrowska, B Lukomska… - Advanced …, 2021 - Wiley Online Library
Neurological disorders are becoming a growing burden as society ages, and there is a
compelling need to address this spiraling problem. Stem cell‐based regenerative medicine …

[HTML][HTML] Mesenchymal stem cells for regenerative medicine

Y Han, X Li, Y Zhang, Y Han, F Chang, J Ding - Cells, 2019 - mdpi.com
In recent decades, the biomedical applications of mesenchymal stem cells (MSCs) have
attracted increasing attention. MSCs are easily extracted from the bone marrow, fat, and …

[HTML][HTML] Mesenchymal stem/stromal cell-derived exosomes for immunomodulatory therapeutics and skin regeneration

DH Ha, H Kim, J Lee, HH Kwon, GH Park, SH Yang… - Cells, 2020 - mdpi.com
Exosomes are nano-sized vesicles that serve as mediators for cell-to-cell communication.
With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the …

[HTML][HTML] Stem cell therapy: from idea to clinical practice

M Mousaei Ghasroldasht, J Seok, HS Park… - International journal of …, 2022 - mdpi.com
Regenerative medicine is a new and promising mode of therapy for patients who have
limited or no other options for the treatment of their illness. Due to their pleotropic therapeutic …

Adult mesenchymal stem cells and their exosomes: Sources, characteristics, and application in regenerative medicine

M Maqsood, M Kang, X Wu, J Chen, L Teng, L Qiu - Life sciences, 2020 - Elsevier
Human mesenchymal stem cells (MSCs) have become a hot topic in the development of cell
therapies and bioengineering. All kinds of MSCs are genomic stable and have the self …

[HTML][HTML] BMSC-derived exosomes promote tendon-bone healing after anterior cruciate ligament reconstruction by regulating M1/M2 macrophage polarization in rats

Z Li, Q Li, K Tong, J Zhu, H Wang, B Chen… - Stem Cell Research & …, 2022 - Springer
Background Recent studies have shown that bone marrow stromal cell-derived exosomes
(BMSC-Exos) can be used for tissue repair. However, whether the BMSC-Exos can promote …

Cell therapies in the clinic

LLW Wang, ME Janes, N Kumbhojkar… - Bioengineering & …, 2021 - Wiley Online Library
Cell therapies have emerged as a promising therapeutic modality with the potential to treat
and even cure a diverse array of diseases. Cell therapies offer unique clinical and …

Evaluation of the safety and efficacy of using human menstrual blood‐derived mesenchymal stromal cells in treating severe and critically ill COVID‐19 patients: an …

X Xu, W Jiang, L Chen, Z Xu, Q Zhang… - Clinical and …, 2021 - Wiley Online Library
Abstract The coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2) was identified in December 2019 and has …