Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease associated with
synovial tissue proliferation, pannus formation, cartilage destruction, and systemic …

Abstract The COVID-19-, SARS-and MERS-related coronaviruses share many genomic and
structural similarities. However, the SARS-CoV-2 is less pathogenic than SARS-CoV and …

Rheumatoid arthritis (RA) is an autoimmune disease affecting∼ 1% of the general
population. This disease is characterized by persistent articular inflammation and joint …

Acute kidney injury (AKI) is a complex clinical disorder associated with poor outcomes.
Targeted regulation of the degree of inflammation has been a potential strategy for AKI …

Background: Cardiac macrophages (cMPs) are increasingly recognized as important
regulators of myocardial homeostasis and disease, yet the role of noncoding RNA in these …

Bone and bone marrow are among the most frequent metastatic sites of cancer. The
occurrence of bone metastasis is frequently associated with a dismal disease outcome. The …

Sepsis is a host immune disorder induced by infection. It can lead to multiple organ
dysfunction syndrome (MODS), which has high morbidity and mortality. There has been …

Cardiac hypertrophy, initiated by a variety of physiological or pathological stimuli
(hemodynamic or hormonal stimulation or infarction), is a critical early adaptive …

The complement system, professional phagocytes and other cells such as Natural killer cells
and mast cells are among the important components of the innate arm of the immune …

Immune checkpoint inhibitors have revolutionized immunotherapy against various cancers
over the last decade. The use of checkpoint inhibitors results in remarkable re-activation of …