Synovial inflammation in osteoarthritis progression
E Sanchez-Lopez, R Coras, A Torres… - Nature Reviews …, 2022 - nature.com
Osteoarthritis (OA) is a progressive degenerative disease resulting in joint deterioration.
Synovial inflammation is present in the OA joint and has been associated with radiographic …
Synovial inflammation is present in the OA joint and has been associated with radiographic …
Hand osteoarthritis: clinical phenotypes, molecular mechanisms and disease management
M Marshall, FE Watt, TL Vincent… - Nature Reviews …, 2018 - nature.com
Osteoarthritis (OA) is a highly prevalent condition, and the hand is the most commonly
affected site. Patients with hand OA frequently report symptoms of pain, functional limitations …
affected site. Patients with hand OA frequently report symptoms of pain, functional limitations …
Immune contributions to osteoarthritis
Abstract Purpose of the Review Mounting evidence supports a role of low-grade
inflammation in the pathophysiology of osteoarthritis (OA). We review and discuss the role of …
inflammation in the pathophysiology of osteoarthritis (OA). We review and discuss the role of …
Innate immune responses and osteoarthritis
Abstract Purpose of the Review Osteoarthritis (OA) is a chronic, painful joint disease that
affects approximately 40% of adults over 70 year. Age is the strongest predictor of OA, while …
affects approximately 40% of adults over 70 year. Age is the strongest predictor of OA, while …
Hydroxychloroquine effectiveness in reducing symptoms of hand osteoarthritis: a randomized trial
SR Kingsbury, P Tharmanathan, A Keding… - Annals of internal …, 2018 - acpjournals.org
Background: Synovitis is believed to play a role in producing symptoms in persons with
hand osteoarthritis, but data on slow-acting anti-inflammatory treatments are sparse …
hand osteoarthritis, but data on slow-acting anti-inflammatory treatments are sparse …
A deep-learning framework for metacarpal-head cartilage-thickness estimation in ultrasound rheumatological images
MC Fiorentino, E Cipolletta, E Filippucci… - Computers in Biology …, 2022 - Elsevier
Objective Rheumatoid arthritis (RA) is a chronic disease characterized by erosive
symmetrical polyarthritis. Bone and cartilage are the main joint targets of this disease …
symmetrical polyarthritis. Bone and cartilage are the main joint targets of this disease …
Cinnamic Aldehyde, the main monomer component of Cinnamon, exhibits anti‐inflammatory property in OA synovial fibroblasts via TLR4/MyD88 pathway
P Chen, J Zhou, A Ruan, L Zeng, J Liu… - Journal of Cellular and …, 2022 - Wiley Online Library
Cinnamon is a wildly used traditional Chinese herbal medicine for osteoarthritis (OA)
treatment, but the underlying mechanism remains ambiguous. The purpose of this study is to …
treatment, but the underlying mechanism remains ambiguous. The purpose of this study is to …
[HTML][HTML] TNF‑α increases the expression of inflammatory factors in synovial fibroblasts by inhibiting the PI3K/AKT pathway in a rat model of monosodium iodoacetate …
H Li, S Xie, Y Qi, H Li, R Zhang… - Experimental and …, 2018 - spandidos-publications.com
Osteoarthritis is a degenerative disease that often causes patients to experience joint pain
and deformity. It has been demonstrated that tumor necrosis factor (TNF)‑α is associated …
and deformity. It has been demonstrated that tumor necrosis factor (TNF)‑α is associated …
[HTML][HTML] Lack of beneficial effects of low-dose radiation therapy on hand osteoarthritis symptoms and inflammation: a randomised, blinded, sham-controlled trial
MJM Minten, MM Leseman-Hoogenboom… - Osteoarthritis and …, 2018 - Elsevier
Objectives Low-dose radiation therapy (LDRT) is widely used as treatment for osteoarthritis
(OA) in some countries, while relatively unknown in others. Systematic literature review …
(OA) in some countries, while relatively unknown in others. Systematic literature review …
[HTML][HTML] Extraction and identification of synovial tissue-derived exosomes by different separation techniques
P Chen, A Ruan, J Zhou, L Huang, X Zhang… - Journal of orthopaedic …, 2020 - Springer
Objective The aim of this study is to compare the efficiency of different separation techniques
for extracting synovial tissue-derived exosomes. Methods The synovial tissue discarded …
for extracting synovial tissue-derived exosomes. Methods The synovial tissue discarded …