The neuropathogenesis of AIDS

F González-Scarano, J Martín-García - Nature reviews immunology, 2005 - nature.com
HIV-associated dementia (HAD) is an important complication of the central nervous system
in patients who are infected with HIV-1. Although the incidence of HAD has markedly …

Macrophages and their relevance in Human Immunodeficiency Virus Type I infection

H Koppensteiner, R Brack-Werner, M Schindler - Retrovirology, 2012 - Springer
Macrophages are important target cells for the Human Immunodeficiency Virus Type I (HIV-
1) in vivo. Several studies have assessed the molecular biology of the virus in this cell type …

Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: a mechanism for cellular human immunodeficiency virus 1 infection

M Mack, A Kleinschmidt, H Brühl, C Klier, PJ Nelson… - Nature medicine, 2000 - nature.com
The release of microparticles from eukaryotic cells is a well-recognized phenomenon. We
demonstrate here that the chemokine receptor CCR5, the principal co-receptor for …

Viruses, parkinsonism and Parkinson's disease: The past, present and future

V Leta, D Urso, L Batzu, YH Lau, D Mathew… - Journal of Neural …, 2022 - Springer
Parkinsonism secondary to viral infections is not an uncommon occurrence and has been
brought under the spotlight with the spread of severe acute respiratory syndrome …

Cellular reservoirs of HIV-1 and their role in viral persistence

A Alexaki, Y Liu, B Wigdahl - Current HIV research, 2008 - ingentaconnect.com
A major obstacle in human immunodeficiency virus type 1 (HIV-1) eradication is the ability of
the virus to remain latent in a subpopulation of the cells it infects. Latently infected cells can …

[HTML][HTML] Viral parkinsonism

H Jang, DA Boltz, RG Webster, RJ Smeyne - Biochimica et Biophysica Acta …, 2009 - Elsevier
Parkinson's disease is a debilitating neurological disorder characterized that affects 1–2% of
the adult population over 55 years of age. For the vast majority of cases, the etiology of this …

Cells of the central nervous system as targets and reservoirs of the human immunodeficiency virus

S Kramer-Hämmerle, I Rothenaigner, H Wolff, JE Bell… - Virus research, 2005 - Elsevier
The availability of highly active antiretroviral therapies (HAART) has not eliminated HIV-1
infection of the central nervous system (CNS) or the occurrence of HIV-associated …

Identification and cloning of human astrocyte genes displaying elevated expression after infection with HIV-1 or exposure to HIV-1 envelope glycoprotein by rapid …

Z Su, D Kang, Y Chen, O Pekarskaya, W Chao… - Oncogene, 2002 - nature.com
Neurodegeneration and dementia are common complications of AIDS caused by human
immunodeficiency virus type 1 (HIV-1) infection of the central nervous system. HIV-1 target …

Cloning and characterization of HIV-1-inducible astrocyte elevated gene-1, AEG-1

D Kang, Z Su, D Sarkar, L Emdad, DJ Volsky, PB Fisher - Gene, 2005 - Elsevier
We presently describe the full-length cloning and functional characterization of an HIV-1-
inducible gene, astrocyte elevated gene (AEG)-1. Additionally, a novel method is outlined for …

Monocyte maturation, HIV susceptibility, and transmigration across the blood brain barrier are critical in HIV neuropathogenesis

DW Williams, EA Eugenin, TM Calderon… - Journal of leukocyte …, 2012 - academic.oup.com
ABSTRACT HIV continues to be a global health crisis with more than 34 million people
infected worldwide (UNAIDS: Report on the Global AIDS Epidemic 2010, Geneva, World …