Endocrine therapy is the prominent strategy for the treatment of hormone-positive breast
cancers. The emergence of resistance to endocrine therapy is a major health concern …

Background It is critical to understand the mechanisms of human cancers in order to develop
the effective anti-cancer therapeutic strategies. Recent studies indicated that primase …

Osteosarcoma (OS) is a malignant bone carcinoma that affects people in childhood and
adulthood. The heterogeneous nature and chromosomal instability represent certain …

Doxorubicin (DOX) resistance in breast cancer (BC) poses a huge challenge for the
therapeutic effect on BC. Lnc KCNQ1OT1 play crucial roles in chemotherapy resistance …

Background Liquid-liquid phase separation (LLPS) enhances oncogenic signaling
pathways and advances cancer progression, and has been proposed as a promising cancer …

Background Liver hepatocellular carcinoma (LIHC) is the third largest cause of cancer
mortality. Exosomes are vital regulators in the development of cancer. However, the …

ABSTRACT Background Long non-coding RNAs (lncRNAs) have been proved to play a vital
role in pancreatic cancer (PC). However, the role of lncRNA FAM83A-AS1 in PC remains …

Extensive research has been conducted on the application of nanoparticles in the treatment
of cancer and infectious diseases. Due to their exceptional characteristics and flexible …

Oral squamous cell carcinoma (OSCC) is a malignant neoplasm with high mortality and
morbidity. The role of circRNA and its molecular mechanism in OSCC remains largely …

Autophagy, a self-digestion mechanism, has emerged as a promising target in the realm of
cancer therapy, particularly in bladder cancer (BCa), a urological malignancy characterized …