Sex and genotype effects on nutrient-dependent fitness landscapes in Drosophila melanogaster

MF Camus, K Fowler, MWD Piper… - Proceedings of the …, 2017 - royalsocietypublishing.org
The sexes perform different reproductive roles and have evolved sometimes strikingly
different phenotypes. One focal point of adaptive divergence occurs in the context of diet and …

An automated method for the analysis of food intake behaviour in Caenorhabditis elegans

MJ Rodríguez-Palero, A López-Díaz, R Marsac… - Scientific reports, 2018 - nature.com
The study of mechanisms that govern feeding behaviour and its related disorders is a matter
of global health interest. The roundworm Caenorhabditis elegans is becoming a model …

Commonly overlooked factors in biocompatibility studies of neural implants

LS Kumosa - Advanced Science, 2023 - Wiley Online Library
Biocompatibility of cutting‐edge neural implants, surgical tools and techniques, and
therapeutic technologies is a challenging concept that can be easily misjudged. For …

Genetics and pharmacology of longevity: the road to therapeutics for healthy aging

JI Castillo-Quan, KJ Kinghorn, I Bjedov - Advances in Genetics, 2015 - Elsevier
Aging can be defined as the progressive decline in tissue and organismal function and the
ability to respond to stress that occurs in association with homeostatic failure and the …

The Longevity Effect of Tannic Acid in Caenorhabditis elegans: Disposable Soma Meets Hormesis

N Saul, K Pietsch, R Menzel… - … Series A: Biomedical …, 2010 - academic.oup.com
This study shows that exposure to low concentrations of the polyphenol tannic acid (TA)
induces potent life-prolonging properties in Caenorhabditis elegans. In addition, enhanced …

[HTML][HTML] Astragalus polysaccharide extends lifespan via mitigating endoplasmic reticulum stress in the silkworm, Bombyx mori

J Song, M Chen, Z Li, J Zhang, H Hu, X Tong… - Aging and …, 2019 - ncbi.nlm.nih.gov
Abstract The traditional Chinese medicine Astragalus polysaccharide (APS) has been
widely used to improve glucose homeostasis and immunoregulator properties. In recent …

Overexpression of Fatty‐Acid‐β‐Oxidation‐Related Genes Extends the Lifespan of Drosophila melanogaster

SH Lee, SK Lee, D Paik, KJ Min - Oxidative medicine and …, 2012 - Wiley Online Library
A better understanding of the aging process is necessary to ensure that the healthcare
needs of an aging population are met. With the trend toward increased human life …

FGT-1 is the major glucose transporter in C. elegans and is central to aging pathways

Y Feng, BG Williams, F Koumanov… - Biochemical …, 2013 - portlandpress.com
Caenorhabditis elegans is widely used as a model for investigation of the relationships
between aging, nutrient restriction and signalling via the DAF-2 (abnormal dauer formation …

Dietary restriction affects lifespan but not cognitive aging in Drosophila melanogaster

JMS Burger, SD Buechel, TJ Kawecki - Aging cell, 2010 - Wiley Online Library
Dietary restriction extends lifespan in a wide variety of animals, including Drosophila, but its
relationship to functional and cognitive aging is unclear. Here, we study the effects of dietary …

Nutraceutical interventions for promoting healthy aging in invertebrate models

Y Dong, S Guha, X Sun, M Cao… - … medicine and cellular …, 2012 - Wiley Online Library
Aging is a complex and inevitable biological process that is associated with numerous
chronically debilitating health effects. Development of effective interventions for promoting …