Stroke has caused tremendous social stress worldwide, yet despite decades of research
and development of new stroke drugs, most have failed and rt-PA (Recombinant tissue …

Pyroptosis is commonly induced by the gasdermin (GSDM) family and is accompanied by
the release of inflammatory cytokines such as IL-1β and IL-18. Recently, increasing …

Bronchial asthma is a complex heterogeneous airway disease, which has emerged as a
global health issue. A comprehensive understanding of the different molecular mechanisms …

Abstract Background Dehydroandrographolide (Deh) from Andrographis paniculata (Burm.
f.) Wall has strong anti-inflammatory and antioxidant activities. Purpose To explore the role …

Epilepsy, a fairly common neurological disorder, is linked to various sequelae and greatly
impairs the quality of life. Meanwhile, there is evidence to suggest an association between …

Schisandra chinensis fruit is a widely edible and medicinal resource, whose extract had a
good inhibitory effect on airway inflammation in asthmatic mice. However, the main active …

Background Tuo-Min-Ding-Chuan Decoction (TMDCD) is an effective traditional Chinese
medicine (TCM) formula granule for allergic asthma (AA). Previous studies proved its effects …

Schizandrin B (SchB) protects against oxidative, inflammatory, and ferroptotic injury.
Oxidative stress and inflammation are indispensably involved in nephrolithiasis and …

Background Schisandrin B (Sch B), the main ingredient of Schisandra chinensis, displays
many bioactivities. This study aimed to identify the drug target of Sch B against liver fibrosis …

As a chronic respiratory disease, asthma is related to airway inflammation and remodeling.
Macrophages are regarded as main innate immune cells in the airway that exert various …