HMGB1 is a member of highly conserved high mobility group protein superfamily with
intracellular and extracellular distribution. Abnormal HMGB1 levels are frequently …

Regulated cell death (RCD) is considered a critical pathway in cancer therapy, contributing
to eliminating cancer cells and influencing treatment outcomes. The application of RCD in …

The miR-34a and miR-34b/c encoding genes represent direct targets of the p53 transcription
factor, and presumably mediate part of the tumor suppressive effects of p53. Here, we …

T lymphocytes served as immune surveillance to suppress metastases by physically
interacting with cancer cells. Whereas tumor immune privilege and heterogeneity protect …

In this work, we describe a novel ruthenium-xanthoxylin complex,[Ru (phen) 2
(xant)](PF6)(RXC), that can eliminate colorectal cancer (CRC) stem cells by targeting the …

Mild‐temperature photothermal therapy (MPTT) is a promising tumor therapeutic modality
because it can avoid the damage of normal tissues near the tumor caused by excessive …

Pancreatic ductal adenocarcinoma (PDAC) features high recurrence rates and intensified
lethality, accompanied by stiffening of the extracellular matrix (ECM) microenvironment …

Ferroptosis is an iron ion-dependent, regulatory cell death modality driven by intracellular
lipid peroxidation that plays a key role in the development of HCC. Studies have shown that …

Autophagy induction is responsible for the chemoresistance of histone deacetylase (HDAC)
inhibitors. The combination of HDAC inhibitors with autophagy inhibitors has been …

Photothermal therapy (PTT) has been proposed as an advanced patient-centered strategy
for tumor treatment. Nevertheless, the uncertain safety of conventional photothermal …