Pharmacological models and approaches for pathophysiological conditions associated with hypoxia and oxidative stress
Hypoxia is the failure of oxygenation at the tissue level, where the reduced oxygen delivered
is not enough to satisfy tissue demands. Metabolic depression is the physiological …
is not enough to satisfy tissue demands. Metabolic depression is the physiological …
Computational fluid dynamics in brain aneurysms
DM Sforza, CM Putman… - International journal for …, 2012 - Wiley Online Library
Because of its ability to deal with any geometry, image‐based computational fluid dynamics
(CFD) has been progressively used to investigate the role of hemodynamics in the …
(CFD) has been progressively used to investigate the role of hemodynamics in the …
Growth and remodeling of load-bearing biological soft tissues
CJ Cyron, JD Humphrey - Meccanica, 2017 - Springer
The past two decades reveal a growing role of continuum biomechanics in understanding
homeostasis, adaptation, and disease progression in soft tissues. In this paper, we briefly …
homeostasis, adaptation, and disease progression in soft tissues. In this paper, we briefly …
On constitutive descriptors of the biaxial mechanical behaviour of human abdominal aorta and aneurysms
J Ferruzzi, DA Vorp… - Journal of the Royal …, 2011 - royalsocietypublishing.org
The abdominal aorta (AA) in older individuals can develop an aneurysm, which is of
increasing concern in our ageing population. The structural integrity of the ageing aortic …
increasing concern in our ageing population. The structural integrity of the ageing aortic …
A theoretical and non-destructive experimental approach for direct inclusion of measured collagen orientation and recruitment into mechanical models of the artery …
Gradual collagen recruitment has been hypothesized as the underlying mechanism for the
mechanical stiffening with increasing stress in arteries. In this work, we investigated this …
mechanical stiffening with increasing stress in arteries. In this work, we investigated this …
Constitutive framework for the modeling of damage in collagenous soft tissues with application to arterial walls
D Balzani, S Brinkhues, GA Holzapfel - Computer Methods in Applied …, 2012 - Elsevier
In this paper a new material model is proposed for the description of stress-softening
observed in cyclic tension tests of collagenous soft tissues such as arterial walls, for applied …
observed in cyclic tension tests of collagenous soft tissues such as arterial walls, for applied …
Methods for thermally-induced hepatic neuromodulation
BR Azamian, SB Vafai, JA Coe - US Patent 8,568,399, 2013 - Google Patents
US8568399B2 - Methods for thermally-induced hepatic neuromodulation - Google Patents
US8568399B2 - Methods for thermally-induced hepatic neuromodulation - Google Patents …
US8568399B2 - Methods for thermally-induced hepatic neuromodulation - Google Patents …
The role of elastin and collagen in the softening behavior of the human thoracic aortic media
H Weisbecker, C Viertler, DM Pierce… - Journal of …, 2013 - Elsevier
In a previous study we were able to accurately fit experimental data on arterial tissues at
supra-physiological loads using a material model that accounts for softening/damage only in …
supra-physiological loads using a material model that accounts for softening/damage only in …
Selective enzymatic removal of elastin and collagen from human abdominal aortas: Uniaxial mechanical response and constitutive modeling
The ability to selectively remove the structurally most relevant components of arterial wall
tissues such as collagen and elastin enables ex vivo biomechanical testing of the remaining …
tissues such as collagen and elastin enables ex vivo biomechanical testing of the remaining …
Biomechanical relevance of the microstructure in artery walls with a focus on passive and active components
GA Holzapfel, RW Ogden - American Journal of Physiology …, 2018 - journals.physiology.org
The microstructure of arteries, consisting, in particular, of collagen, elastin, and vascular
smooth muscle cells, plays a very significant role in their biomechanical response during a …
smooth muscle cells, plays a very significant role in their biomechanical response during a …