Understanding how the homeostatic stress state can be reached in arterial tissues can
provide new insights into vascular physiology. Even though the function of maintaining …

We consider the mechanics of fiber remodeling in a pressurized thick walled cylinder where
our focus is on the interaction between inflation and remodeling. The material is taken to …

According to Some embodiments, a method of treating a Subject having diabetes or
symptoms associated with diabetes is provided. The method includes delivering a …

Decreased elastin in mice (Eln+/−) yields a functioning vascular system with elevated blood
pressure and increased arterial stiffness that is morphologically distinct from wild-type mice …

According to Some embodiments, a method of treating a Subject having diabetes or
symptoms associated with diabetes is provided. The method includes delivering a …

During the progression of pulmonary hypertension (PH), proximal pulmonary arteries (PAs)
increase in both thickness and stiffness. Collagen, a component of the extracellular matrix, is …

Arterial wall tissues are sensitive to their mechanical surroundings and remodel their
structure and mechanical properties when subjected to mechanical stimuli such as …

Studies on the influence of aging on the longitudinal mechanical response of elastic arteries
are rare, though longitudinal behavior may have a significant effect on pressure pulse …

The main components responsible for the mechanical behavior of the arterial wall are
collagen, elastin, and smooth muscle cells (SMCs) in the medial layer. We determined the …

(. 01) 7,756,583 B2 7/2010 Demarais et al. A6B 7/00(2006.01) 7,769,470 B1 8/2010 Rezai
A6 IB 8/06(2006.01) 7,778,704 B2 8, 2010 Rezai A61N 7700(2006.01) 7,831,308 B2 …