[HTML][HTML] Role of precision medicine and personalized medicine in the treatment of diseases

M Farrokhi, F Taheri, PJ Khouzani, E Rahmani… - Kindle, 2023 - preferpub.org
Precision medicine and personalized medicine are two approaches to healthcare that aim to
tailor medical treatments and interventions to individual patients. These approaches are …

The role of lncRNAs in intermittent hypoxia and sleep Apnea: A review of experimental and clinical evidence

MT Moradi, R Fadaei, A Sharafkhaneh, H Khazaie… - Sleep Medicine, 2023 - Elsevier
In this narrative review, we present a comprehensive assessment on the putative roles of
long non-coding RNAs (lncRNAs) in intermittent hypoxia (IH) and sleep apnea. Collectively …

A Review of Novel Oximetry Parameters for the Prediction of Cardiovascular Disease in Obstructive Sleep Apnoea

S He, PA Cistulli, P de Chazal - Diagnostics, 2023 - mdpi.com
Obstructive sleep apnoea (OSA) is a sleep disorder with repetitive collapse of the upper
airway during sleep, which leads to intermittent hypoxic events overnight, adverse …

ERS International Congress 2023: highlights from the Sleep Disordered Breathing Assembly

M Siciliano, M Bradicich, P Tondo… - ERJ Open …, 2024 - Eur Respiratory Soc
The topic of sleep-related breathing disorders is always evolving, and during the European
Respiratory Society (ERS) International Congress 2023 in Milan, Italy, the latest research …

The advent of RNA-based therapeutics for metabolic syndrome and associated conditions: a comprehensive review of the literature

HYR Huang, S Badar, M Said, S Shah… - Molecular Biology …, 2024 - Springer
Metabolic syndrome (MetS) is a prevalent and intricate health condition affecting a
significant global population, characterized by a cluster of metabolic and hormonal disorders …

All Obstructive Sleep Apnea Events Are Not Created Equal: The Relationship between Event-related Hypoxemia and Physiologic Response

M Hajipour, AJ Hirsch Allen, AE Beaudin… - Annals of the …, 2024 - atsjournals.org
Rationale: Obstructive sleep apnea (OSA) severity is typically assessed by the apnea–
hypopnea index (AHI), a frequency-based metric that allocates equal weight to all …

Relationship between obstructive sleep apnea and pulmonary hypertension: past, present and future

J Lenka, R Foley, M Metersky… - Expert Review of …, 2024 - Taylor & Francis
Introduction Obstructive sleep apnea (OSA) is a widely prevalent condition with consequent
multiple organ systems complications. There is consensus that OSA is associated with …

Revolutionising obstructive sleep apnoea therapy: polysomnography unveils hidden clues to help provide precision care

C Heiser, NT Ayas - European Respiratory Journal, 2024 - Eur Respiratory Soc
Extract Obstructive sleep apnoea (OSA), a condition that plagues almost a billion individuals
worldwide, is notoriously difficult to treat due to its complex and varied nature [1]. Traditional …

Personalizing obstructive sleep apnea therapy using machine learning: insights from the ISAACC trial

AS BaHammam - Annals of the American Thoracic Society, 2024 - atsjournals.org
Although continuous positive airway pressure (CPAP) is the mainstay treatment for OSA, its
efficacy in preventing primary or secondary CVD events has not been consistently …

Inflammation and Continuous Positive Airway Pressure Therapy: More Evidence of the Need for Better Sleep Apnea Phenotyping

S Redline, DJ Gottlieb - Annals of the American Thoracic Society, 2023 - atsjournals.org
Clinical and epidemiological research in recent decades has established that obstructive
sleep apnea (OSA) is prevalent (1) and is associated with an increased risk for excessive …