Antifungal drugs

J Houšť, J Spížek, V Havlíček - Metabolites, 2020 - mdpi.com
We reviewed the licensed antifungal drugs and summarized their mechanisms of action,
pharmacological profiles, and susceptibility to specific fungi. Approved antimycotics inhibit 1 …

[PDF][PDF] Hope on the horizon: novel fungal treatments in development

AM Rauseo, A Coler-Reilly, L Larson… - Open forum infectious …, 2020 - academic.oup.com
The treatment of invasive fungal infections remains challenging due to limitations in currently
available antifungal therapies including toxicity, interactions, restricted routes of …

The application of isatin-based multicomponent-reactions in the quest for new bioactive and druglike molecules

P Brandao, C Marques, AJ Burke, M Pineiro - European journal of …, 2021 - Elsevier
Oxindole derivatives are known for their great interest in the field of Medicinal Chemistry, as
they display vast biological activities. Recent efforts concerning the preparation of oxindole …

[HTML][HTML] Antifungal peptides as therapeutic agents

M Fernández de Ullivarri, S Arbulu… - Frontiers in Cellular …, 2020 - frontiersin.org
Fungi have been used since ancient times in food and beverage-making processes and,
more recently, have been harnessed for the production of antibiotics and in processes of …

Effects of Ce doping on the Fenton-like reactivity of Cu-based catalyst to the fluconazole

N Zhang, Y Yi, J Lian, Z Fang - Chemical Engineering Journal, 2020 - Elsevier
In order to fully exploit the potential of Cu-based Fenton systems, Ce was utilized to modify
the Cu-based catalysts through one-pot synthesis. A typical antifungal drug, fluconazole …

[HTML][HTML] Development and research progress of anti-drug resistant fungal drugs

X Cui, L Wang, Y Lue, C Yue - Journal of Infection and Public Health, 2022 - Elsevier
With the widespread use of immunosuppressive agents and the increase in patients with
severe infections, the incidence of fungal infections worldwide has increased year by year …

Bladder cancer stage-associated hub genes revealed by WGCNA co-expression network analysis

Y Di, D Chen, W Yu, L Yan - Hereditas, 2019 - Springer
Background Bladder cancer was a malignant disease in patients, our research aimed at
discovering the possible biomarkers for the diseases. Results The gene chip GSE31684 …

Tetrazole hybrids and their antifungal activities

SQ Wang, YF Wang, Z Xu - European journal of medicinal chemistry, 2019 - Elsevier
Fungi, which can cause serious infections, results in more than 1.35 million deaths annually
throughout the world. Azole antifungal drugs which could inhibit the enzyme lanosterol 14α …

[HTML][HTML] Novel promising antifungal target proteins for conquering invasive fungal infections

C Zhen, H Lu, Y Jiang - Frontiers in microbiology, 2022 - frontiersin.org
Invasive fungal infections (IFIs) pose a serious clinical problem, but the antifungal arsenal is
limited and has many disadvantages, such as drug resistance and toxicity. Hence, there is …

Efficient oxidative degradation of fluconazole by a heterogeneous Fenton process with Cu-V bimetallic catalysts

N Zhang, C Xue, K Wang, Z Fang - Chemical Engineering Journal, 2020 - Elsevier
In this study, a novel Cu-V bimetallic catalyst (CuVOx) with abundant surface defects was
successfully synthesized by hydrothermal method. Degradation experiment of emerging …