Therapeutic effects of synthetic triblock amphiphilic short antimicrobial peptides on human lung adenocarcinoma

D Yang, L Zhu, X Lin, J Zhu, Y Qian, W Liu, J Chen… - Pharmaceutics, 2022 - mdpi.com
Because of their unique properties, antimicrobial peptides (AMPs) represent a potential
reservoir of novel anticancer therapeutic agents. However, only a few AMPs can kill tumors …

The interaction between Carbohydrates and the Antimicrobial Peptide P-113Tri is Involved in the Killing of Candida albicans

GY Lin, CF Chang, CY Lan - Microorganisms, 2020 - mdpi.com
The emergence of drug resistance to Candida albicans is problematic in the clinical setting.
Therefore, developing new antifungal drugs is in high demand. Our previous work indicated …

Exploring the Fluconazole‐Resistance Modifying Activity and Potential Mechanism of Action of Fixed Oil from Caryocar coriaceum Wittm.(Caryocaraceae) against …

JW Almeida‐Bezerra, R Pereira da Cruz… - Chemistry & …, 2024 - Wiley Online Library
The fixed oil from the inner mesocarp of Caryocar coriaceum Wittm. is used in the Chapada
do Araripe region of Brazil for the treatment of genitourinary candidiasis. This study aimed to …

N-alkylated linear heptamethine polyenes as potent non-azole leads against Candida albicans fungal infections

CL Lawrence, AO Okoh, V Vishwapathi… - Bioorganic …, 2020 - Elsevier
In this study, eighteen heptamethine dyes were synthesised and their antifungal activities
were evaluated against three clinically relevant yeast species.. The eighteen dyes were …

Antimicrobial and antibiofilm activities of Inga cylindrica trypsin inhibitor

APR Pereira, AC Jacobowski, JCO Sardi… - Brazilian Journal of …, 2024 - SciELO Brasil
Inga cylindrica, a tropical fruit tree of the Fabaceae family (subfamily Mimosoideae), is native
to South America. The seeds from this family are an essential source of trypsin inhibitors …

[PDF][PDF] Synthesis of (S)-alanyl-(S)-β-(thiazol-2-yl-carbamoyl)-α-alanine, dipeptide containing it and in vitro investigation of the antifungal activity

H Hakobyan, Z Mardiyan, N Khachaturyan… - …, 2022 - farmaciajournal.com
Abstract Enantiomerically enriched (S)-β-(thiazol-2-yl-carbamoyl)-α-alanine amino acid was
synthesized by the method of asymmetric synthesis, Ni (II) planar complex of glycine was …

[PDF][PDF] 纳米颗粒在抗菌药物剂型开发中的研究进展

刘尔越, 陆宇 - 中国抗生素杂志, 2023 - zgkss.com.cn
纳米结构生物材料, 特别是纳米颗粒(nanoparticles, NPs), 具有独特的理化性质,
如超小且可控的尺寸, 高比表面积和可经修饰功能化的结构等. 这些特性有助于开发抗菌药物新 …

Therapeutic approaches for combating aspergillus associated infection

A Punia, P Choudhary, N Sharma, S Dahiya… - Current Drug …, 2022 - ingentaconnect.com
Now-a-days fungal infection emerges as a significant problem to healthcare management
systems due to high frequency of associated morbidity, mortality toxicity, drug-drug …

One Century of Study: What We Learned about Paracoccidioides and How This Pathogen Contributed to Advances in Antifungal Therapy

E Seki Kioshima, P de Souza Bonfim de Mendonça… - Journal of Fungi, 2021 - mdpi.com
Paracoccidioidomycosis (PCM) is a notable fungal infection restricted to Latin America.
Since the first description of the disease by Lutz up to the present day, Brazilian researchers …

Discovery of a novel and selective fungicide that targets fungal cell wall to treat dermatomycoses: 1, 3‐bis (3, 4‐dichlorophenoxy) propan‐2‐aminium chloride

D Flores Dalla Lana, S Neiva Lavorato… - Mycoses, 2020 - Wiley Online Library
Background Fungal infections are highly prevalent and are responsible for high rates of
morbidity and mortality. In this context, the search for new treatment alternatives is very …