Epigenetic and genetic factors related to curve progression in adolescent idiopathic scoliosis: a systematic scoping review of the current literature

C Faldini, M Manzetti, S Neri, F Barile, G Viroli… - International journal of …, 2022 - mdpi.com
Adolescent idiopathic scoliosis (AIS) is a progressive deformity of the spine. Scoliotic curves
progress until skeletal maturity leading, in rare cases, to a severe deformity. While the Cobb …

[HTML][HTML] Etiopathogenesis of adolescent idiopathic scoliosis: Review of the literature and new epigenetic hypothesis on altered neural crest cells migration in early …

AM Zaydman, EL Strokova, NY Pahomova, AF Gusev… - Medical …, 2021 - Elsevier
Adolescent idiopathic scoliosis (AIS) affects 2–3% of children. Numerous hypotheses on
etiologic/causal factors of AIS were investigated, but all failed to identify therapeutic targets …

Risk factors, lifestyle and prevention among adolescents with idiopathic juvenile scoliosis: a cross sectional study in eleven first-grade secondary schools of Palermo …

D Scaturro, C Costantino, P Terrana… - International journal of …, 2021 - mdpi.com
Adolescent idiopathic scoliosis (AIS) has an incidence of 2–3% in the general population
and a multifactorial etiology. The present study aims to analyze modifiable risk factors and …

Exploring the association between specific genes and the onset of idiopathic scoliosis: a systematic review

S De Salvatore, L Ruzzini, UG Longo, M Marino… - BMC Medical …, 2022 - Springer
Abstract Background Idiopathic Scoliosis (IS) is the most common spinal deformity in
adolescents, accounting for 80% of all spinal deformities. However, the etiology remains …

The potential role of dysregulated miRNAs in adolescent idiopathic scoliosis and 22q11. 2 deletion syndrome

N Montemurro, L Ricciardi, A Scerrati… - Journal of Personalized …, 2022 - mdpi.com
Background: Adolescent idiopathic scoliosis (AIS), affecting 2–4% of adolescents, is a
multifactorial spinal disease. Interactions between genetic and environmental factors can …

Is scoliosis related to mastication muscle asymmetry and temporomandibular disorders? A cross-sectional study

İ Uçar, S Batın, M Arık, A Payas, E Kurtoğlu… - … Science and Practice, 2022 - Elsevier
Objective Patients with adolescent idiopathic scoliosis (AIS) may face motor control
problems and health disability barriers during mandibular movements and chewing …

Academic-related factors and daily lifestyle habits associated with adolescent idiopathic scoliosis: a case-control study

Q Dou, Z Zhu, L Zhu, W Wang, L Guo, S Ru… - … Health and Preventive …, 2023 - jstage.jst.go.jp
Background: Adolescent idiopathic scoliosis (AIS) is the most prevalent spinal deformity,
which may have long-term negative consequences on adolescents. The research on the …

FTO-dependent m6A regulates muscle fiber remodeling in an NFATC1–YTHDF2 dependent manner

W Wang, X Du, M Luo, N Yang - Clinical Epigenetics, 2023 - Springer
Background Adolescent idiopathic scoliosis (AIS) is characterized by low lean mass without
vertebral deformity. The cause-and-effect relationship between scoliosis and paraspinal …

Whole exome sequencing of 23 multigeneration idiopathic scoliosis families reveals enrichments in cytoskeletal variants, suggests highly polygenic disease

EA Terhune, CI Wethey, MT Cuevas, AM Monley… - Genes, 2021 - mdpi.com
Adolescent idiopathic scoliosis (AIS) is a lateral spinal curvature> 10° with rotation that
affects 2–3% of healthy children across populations. AIS is known to have a significant …

Associations of physical activity and screen time with adolescent idiopathic scoliosis

L Zhu, S Ru, W Wang, Q Dou, Y Li, L Guo… - … Health and Preventive …, 2023 - jstage.jst.go.jp
Background: Adolescent idiopathic scoliosis (AIS) is the most common type of idiopathic
scoliosis, affecting approximately 0.61%–6.15% adolescents worldwide. To date, the results …