[HTML][HTML] Stem cell-based therapy for human diseases
DM Hoang, PT Pham, TQ Bach, ATL Ngo… - Signal transduction and …, 2022 - nature.com
Recent advancements in stem cell technology open a new door for patients suffering from
diseases and disorders that have yet to be treated. Stem cell-based therapy, including …
diseases and disorders that have yet to be treated. Stem cell-based therapy, including …
[HTML][HTML] Cellular mechanotransduction in health and diseases: from molecular mechanism to therapeutic targets
Cellular mechanotransduction, a critical regulator of numerous biological processes, is the
conversion from mechanical signals to biochemical signals regarding cell activities and …
conversion from mechanical signals to biochemical signals regarding cell activities and …
[HTML][HTML] Notoginsenoside R1-loaded mesoporous silica nanoparticles targeting the site of injury through inflammatory cells improves heart repair after myocardial …
H Li, J Zhu, Y Xu, F Mou, X Shan, Q Wang, B Liu… - Redox Biology, 2022 - Elsevier
Abstract Notoginsenoside R1 (NGR1) is the main monomeric component extracted from the
dried roots and rhizomes of Panax notoginseng, and exerts pharmacological action against …
dried roots and rhizomes of Panax notoginseng, and exerts pharmacological action against …
[HTML][HTML] Signaling pathways and targeted therapies for psoriasis
J Guo, H Zhang, W Lin, L Lu, J Su… - Signal Transduction and …, 2023 - nature.com
Psoriasis is a common, chronic, and inflammatory skin disease with a high burden on
individuals, health systems, and society worldwide. With the immunological pathologies and …
individuals, health systems, and society worldwide. With the immunological pathologies and …
[HTML][HTML] Advances in the study of exosomes derived from mesenchymal stem cells and cardiac cells for the treatment of myocardial infarction
Y Liu, M Wang, Y Yu, C Li, C Zhang - Cell Communication and Signaling, 2023 - Springer
Acute myocardial infarction has long been the leading cause of death in coronary heart
disease, which is characterized by irreversible cardiomyocyte death and restricted blood …
disease, which is characterized by irreversible cardiomyocyte death and restricted blood …
Elevated levels of alcohol dehydrogenase aggravate ethanol-evoked cardiac remodeling and contractile anomalies through FKBP5-yap-mediated regulation of …
Q Lu, X Qin, C Chen, W Yu, J Lin, X Liu, R Guo… - Life sciences, 2024 - Elsevier
Alcohol intake provokes severe organ injuries including alcoholic cardiomyopathy with
hallmarks of cardiac remodeling and contractile defects. This study examined the toxicity of …
hallmarks of cardiac remodeling and contractile defects. This study examined the toxicity of …
[HTML][HTML] Exosomes and exosomal cargos: a promising world for ventricular remodeling following myocardial infarction
J Fang, Y Zhang, D Chen, Y Zheng… - International Journal of …, 2022 - ncbi.nlm.nih.gov
Exosomes are a pluripotent group of extracellular nanovesicles secreted by all cells that
mediate intercellular communications. The effective information within exosomes is primarily …
mediate intercellular communications. The effective information within exosomes is primarily …
Notch signalling: multifaceted role in development and disease
N Sachan, V Sharma, M Mutsuddi… - The FEBS …, 2024 - Wiley Online Library
Notch pathway is an evolutionarily conserved signalling system that operates to influence an
astonishing array of cell fate decisions in different developmental contexts. Notch signalling …
astonishing array of cell fate decisions in different developmental contexts. Notch signalling …
[HTML][HTML] Post-myocardial infarction fibrosis: Pathophysiology, examination, and intervention
X Yin, X Yin, X Pan, J Zhang, X Fan, J Li… - Frontiers in …, 2023 - frontiersin.org
Cardiac fibrosis plays an indispensable role in cardiac tissue homeostasis and repair after
myocardial infarction (MI). The cardiac fibroblast-to-myofibroblast differentiation and …
myocardial infarction (MI). The cardiac fibroblast-to-myofibroblast differentiation and …
Recent advances in electrochemical nanobiosensors for cardiac biomarkers
The WHO reports heart diseases, especially MI, are the leading cause of death. During a
heart attack and damage to myocardial cells, cardiac biomarkers are released into the …
heart attack and damage to myocardial cells, cardiac biomarkers are released into the …