Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of
deaths and substantial morbidity worldwide. Intense scientific effort to understand the …

Prostate cancer is the most commonly diagnosed cancer affecting men in the United States.
The prostate is a hormone-dependent gland in which androgen hormones testosterone and …

Nirmatrelvir is a specific antiviral drug that targets the main protease (Mpro) of SARS-CoV-2
and has been approved to treat COVID-19,. As an RNA virus characterized by high mutation …

Since the first antiviral drug, idoxuridine, was approved in 1963, 90 antiviral drugs
categorized into 13 functional groups have been formally approved for the treatment of the …

To improve human immunodeficiency virus (HIV) treatment and prevention, therapeutic
strategies that can provide effective and broad‐spectrum neutralization against viral …

New drug deployment strategies are imperative to address the problem of drug resistance,
which is limiting the management of infectious diseases and cancers. We evolved resistance …

Background Despite declines in morbidity and mortality with the use of combination
antiretroviral therapy, its effectiveness is limited by adverse events, problems with …

SARS-CoV-2 mutations that cause resistance to monoclonal antibody (mAb) therapy have
been reported. However, it remains unclear whether in vivo emergence of SARS-CoV-2 …

Biomedical engineers have traditionally developed technologies in response to the needs of
the developed world's medical community. As a result, the diagnostic systems on which they …

Patients with chronic hepatitis B (CHB) can be successfully treated using nucleos (t) ide
analogs (NA), but drug-resistant hepatitis B virus (HBV) mutants frequently arise, leading to …