Benzannulation strategies for the synthesis of carbazoles, indolocarbazoles, benzocarbazoles, and carbolines
Nitrogen-containing π-excessive aromatic heterocycles, in particular, carbazoles,
indolocarbazoles, benzocarbazoles, and carbolines have been considered the fundamental …
indolocarbazoles, benzocarbazoles, and carbolines have been considered the fundamental …
Recent advances on synthesis and biological activities of aurones
G Sui, T Li, B Zhang, R Wang, H Hao, W Zhou - Bioorganic & Medicinal …, 2021 - Elsevier
Aurones are naturally occurring structural isomerides of flavones that have diverse
bioactivities including antiviral, antibacterial, antifungal, anti-inflammatory, antitumor …
bioactivities including antiviral, antibacterial, antifungal, anti-inflammatory, antitumor …
[HTML][HTML] Stereodivergent assembly of tetrahydro-γ-carbolines via synergistic catalytic asymmetric cascade reaction
SM Xu, L Wei, C Shen, L Xiao, HY Tao… - Nature …, 2019 - nature.com
Enantiomerically enriched indole-containing heterocycles play a vital role in bioscience,
medicine, and chemistry. As one of the most attractive subtypes of indole alkaloids, highly …
medicine, and chemistry. As one of the most attractive subtypes of indole alkaloids, highly …
[HTML][HTML] 1, 3, 4-Oxadiazole-containing hybrids as potential anticancer agents: Recent developments, mechanism of action and structure-activity relationships
S Nayak, SL Gaonkar, EA Musad… - Journal of Saudi Chemical …, 2021 - Elsevier
Chemotherapy is an important therapeutic approach for the treatment of cancer. Currently,
many anticancer drugs are available in the market that plays an important role in cancer …
many anticancer drugs are available in the market that plays an important role in cancer …
Recent advances on the synthesis and application of tetrahydro-γ-carbolines
Tetrahydro-γ-carbolines (THγ Cs) constitute one of the most important subtypes of indole
alkaloids. In addition to being substructures of natural products, these structural motifs and …
alkaloids. In addition to being substructures of natural products, these structural motifs and …
Visible-light-irradiated cascade reaction of indole-tethered alkenes to access tetracyclic tetrahydro-γ-carbolines
A series of indole-derived alkenes have been designed and applied in a photocatalytic
cascade reaction with bromodifluoroacetate esters, affording an unknown type of tetracyclic …
cascade reaction with bromodifluoroacetate esters, affording an unknown type of tetracyclic …
Carboline regioisomers based on unified synthetic approaches
ASM Arshad, MN Mordi - Advanced Synthesis & Catalysis, 2023 - Wiley Online Library
Carbolines are a prominent class of tricyclic alkaloids omnipresent in natural products and
bioactive compounds. Four different carboline regioisomers are known (α‐, β‐, γ‐, and δ …
bioactive compounds. Four different carboline regioisomers are known (α‐, β‐, γ‐, and δ …
[HTML][HTML] Modular assembly of indole alkaloids enabled by multicomponent reaction
Indole alkaloids are one of the largest alkaloid classes, proving valuable structural moiety in
pharmaceuticals. Although methods for the synthesis of indole alkaloids are constantly …
pharmaceuticals. Although methods for the synthesis of indole alkaloids are constantly …
Rapid Access to Fused Tetracyclic N-Heterocycles via Amino-to-Alkyl 1,5-Palladium Migration Coupled with Intramolecular C(sp3)–C(sp2) Coupling
D Chen, J Li, X Zhang, G Liu, X Wang, Y Liu, X Liu… - Organic …, 2023 - ACS Publications
An unprecedented route for the preparation of fused tetracyclic N-heterocycles is presented
through the palladium-catalyzed cyclization of isocyanides with alkyne-tethered aryl iodides …
through the palladium-catalyzed cyclization of isocyanides with alkyne-tethered aryl iodides …
Hydroxamic acid hybrids as the potential anticancer agents: An Overview
W Liu, Y Liang, X Si - European Journal of Medicinal Chemistry, 2020 - Elsevier
Hydroxamic acid derivatives are potential histone deacetylase inhibitors, and several
hydroxamic acid-based histone deacetylase inhibitors have already been used clinically as …
hydroxamic acid-based histone deacetylase inhibitors have already been used clinically as …