[HTML][HTML] Melatonin, BAG-1 and cortisol circadian interactions in tumor pathogenesis and patterned immune responses

G Anderson - Exploration of targeted anti-tumor therapy, 2023 - ncbi.nlm.nih.gov
A dysregulated circadian rhythm is significantly associated with cancer risk, as is aging. Both
aging and circadian dysregulation show suppressed pineal melatonin, which is indicated in …

[HTML][HTML] Role of the epithelial barrier in intestinal fibrosis associated with inflammatory bowel disease: relevance of the epithelial-to mesenchymal transition

DC Macias-Ceja, MT Mendoza-Ballesteros… - Frontiers in Cell and …, 2023 - frontiersin.org
In inflammatory bowel disease (IBD), chronic inflammation in the gastrointestinal tract can
lead to tissue damage and remodelling, which can ultimately result in fibrosis. Prolonged …

Review of METTL3 in colorectal cancer: From mechanisms to the therapeutic potential

L Zhang, Z Mao, K Yin, S Wang - International Journal of Biological …, 2024 - Elsevier
Abstract N6-methyladenosine (m 6 A), the most abundant modification in mRNAs, affects the
fate of the modified RNAs at the post-transcriptional level and participants in various …

[HTML][HTML] Intestinal Fibrogenesis in Inflammatory Bowel Diseases: Exploring the Potential Role of Gut Microbiota Metabolites as Modulators

S Cicchinelli, S Gemma, G Pignataro, A Piccioni… - Pharmaceuticals, 2024 - mdpi.com
Fibrosis, sustained by the transformation of intestinal epithelial cells into fibroblasts
(epithelial-to-mesenchymal transition, EMT), has been extensively studied in recent …

Macrophage Migration Inhibitory Factor (MIF) Upregulates CXCR7 and Contributes to Chemotherapy Resistance in Colorectal Cancer

S Hu, J Feng, W Fu, Y Guo - Cell Biochemistry and Biophysics, 2024 - Springer
Colorectal cancer is one of the most common malignant tumors worldwide, with high
incidence and mortality rates making it a focus of research. Chemotherapy is a primary …

The roles of gut microbiota metabolites in the occurrence and development of colorectal cancer: Multiple insights for potential clinical applications

W Cheng, F Li, R Yang - Gastro Hep Advances, 2024 - Elsevier
Colorectal cancer (CRC) is one of the most common cancers worldwide. The occurrence
and development of CRC are related to multiple risk factors such as gut microbiota. Indeed …

[HTML][HTML] Clostridium bacteria: The team of microscopic oncologists

R Behboodi, A Saadati Partan, S Meidaninikjeh… - Iranian Journal of Blood …, 2023 - ijbc.ir
As we approach the year 2023, the global rise in cancer mortality remains a pressing
concern. Recent studies have demonstrated the remarkable potential of bacteria in …