The ovarian follicle provides the oocyte with the ideal environment for growth and
development in preparation for ovulation and fertilisation. The follicle undergoes many …

Although mammalian embryo development may be considered strictly to begin with the
formation of an oocyte, and progresses through implantation, organogenesis, and fetal …

As with most cells, bovine pre-elongation embryos are highly dependent on oxidative
phosphorylation as the primary energy production pathway (that is, ATP generating …

Nitric oxide (NO), a modulator of several physiological processes, is involved in different
human sperm functions. We have investigated whether NO may stimulate the motility of …

Although intracellular pH (pHi), is a regulator of numerous biological processes, it has
received relatively little attention with regard to the physiology of the mammalian …

It has been suggested that during mouse preimplantation development, the zygotically
expressed transcription factor TEAD4 is essential for specification of the trophectoderm …

The biology of preimplantation embryo gene expression began 56 years ago with studies of
the effects of protein synthesis inhibition and discovery of changes in embryo metabolism …

Oocytes within antral follicles are thought to have restricted access to O2, as follicle
vascularity is not adjacent and both granulosa and cumulus cells are metabolically active …

Unicellular organisms are exquisitely sensitive to nutrient availability in the environment and
have evolved elaborate mechanisms to sense the levels and types of nutrients, altering …

Measuring the metabolism of early embryos has the potential to be used as a prospective
marker for post-transfer development, either alone or in conjunction with other embryo …