[HTML][HTML] Silica nanoparticles: A review of their safety and current strategies to overcome biological barriers
Silica nanoparticles (SNP) have gained tremendous attention in the recent decades. They
have been used in many different biomedical fields including diagnosis, biosensing and …
have been used in many different biomedical fields including diagnosis, biosensing and …
[HTML][HTML] Mucus interaction to improve gastrointestinal retention and pharmacokinetics of orally administered nano-drug delivery systems
DA Subramanian, R Langer, G Traverso - Journal of nanobiotechnology, 2022 - Springer
Oral delivery of therapeutics is the preferred route of administration due to ease of
administration which is associated with greater patient medication adherence. One major …
administration which is associated with greater patient medication adherence. One major …
Current advances in multifunctional nanocarriers based on marine polysaccharides for colon delivery of food polyphenols
S Tie, M Tan - Journal of Agricultural and Food Chemistry, 2022 - ACS Publications
Inflammatory bowel disease (IBD) has been considered as a chronic disease that is difficult
to cure and needs lifelong treatment. Marine polysaccharides with good biocompatibility and …
to cure and needs lifelong treatment. Marine polysaccharides with good biocompatibility and …
Recent advances in oral and transdermal protein delivery systems
Protein and peptide drugs are predominantly administered by injection to achieve high
bioavailability, but this greatly compromises patient compliance. Oral and transdermal drug …
bioavailability, but this greatly compromises patient compliance. Oral and transdermal drug …
Mucus penetration of surface-engineered nanoparticles in various pH microenvironments
The penetration behavior of nanoparticles in mucous depends on physicochemical
properties of the nanoparticles and the mucus microenvironment, due to particle–mucin …
properties of the nanoparticles and the mucus microenvironment, due to particle–mucin …
Bioinspired pH-responsive microalgal hydrogels for oral insulin delivery with both hypoglycemic and insulin sensitizing effects
C Ren, D Zhong, Y Qi, C Liu, X Liu, S Chen, S Yan… - ACS …, 2023 - ACS Publications
The oral form of insulin is more convenient and has better patient compliance than
subcutaneous or intravenous insulin. Current oral insulin preparations, however, cannot …
subcutaneous or intravenous insulin. Current oral insulin preparations, however, cannot …
[HTML][HTML] Advances in oral peptide drug nanoparticles for diabetes mellitus treatment
Y Li, W Zhang, R Zhao, X Zhang - Bioactive Materials, 2022 - Elsevier
Peptide drugs play an important role in diabetes mellitus treatment. Oral administration of
peptide drugs is a promising strategy for diabetes mellitus because of its convenience and …
peptide drugs is a promising strategy for diabetes mellitus because of its convenience and …
Nanocarriers transport across the gastrointestinal barriers: the contribution to oral bioavailability via blood circulation and lymphatic pathway
D Wang, Q Jiang, Z Dong, T Meng, F Hu, J Wang… - Advanced Drug Delivery …, 2023 - Elsevier
Oral administration is the preferred route of drug delivery in clinical practice due to its
noninvasiveness, safety, convenience, and high patient compliance. The gastrointestinal …
noninvasiveness, safety, convenience, and high patient compliance. The gastrointestinal …
[HTML][HTML] Versatile oral insulin delivery nanosystems: from materials to nanostructures
M Wang, C Wang, S Ren, J Pan, Y Wang… - International Journal of …, 2022 - mdpi.com
Diabetes is a chronic metabolic disease characterized by lack of insulin in the body leading
to failure of blood glucose regulation. Diabetes patients usually need frequent insulin …
to failure of blood glucose regulation. Diabetes patients usually need frequent insulin …
Oral Delivery of Protein Drugs via Lysine Polymer‐Based Nanoparticle Platforms
S Han, P Xin, Q Guo, Z Cao… - Advanced Healthcare …, 2023 - Wiley Online Library
Oral delivery of proteins has opened a new perspective for the treatment of different
diseases. However, advances of oral protein formulation are usually hindered by protein …
diseases. However, advances of oral protein formulation are usually hindered by protein …