Photoacoustic imaging of the excited state lifetime of fluorophores

J Märk, FJ Schmitt, J Laufer - Journal of Optics, 2016 - iopscience.iop.org
Photoacoustic (PA) imaging using pump–probe excitation has been shown to allow the
detection and visualization of fluorescent contrast agents. The technique relies upon …

Dual-wavelength photoacoustic imaging of a photoswitchable reporter protein

H Dortay, J Märk, A Wagener, E Zhang… - … and Sensing 2016, 2016 - spiedigitallibrary.org
Photoacoustic (PA) imaging has been shown to provide detailed 3-D images of genetically
expressed reporters, such as fluorescent proteins and tyrosinase-induced melanin. Their …

[HTML][HTML] The bright future of nanotechnology in lymphatic system imaging and imaging-guided surgery

S Qi, X Wang, K Chang, W Shen, G Yu, J Du - Journal of …, 2022 - Springer
Lymphatic system is identified the second vascular system after the blood circulation in
mammalian species, however the research on lymphatic system has long been hampered …

Spectral-differential-based unmixing for multispectral photoacoustic imaging

T Hirasawa, RJ Iwatate, M Kamiya, S Okawa… - Applied Optics, 2018 - opg.optica.org
We propose the use of a spectral differential method (SDM) to emphasize the spectral peaks
of multispectral photoacoustic images. Because contrast agent signals have spectral peaks …

Seeing through the surface: non-invasive characterization of biomaterial–tissue interactions using photoacoustic microscopy

YS Zhang, LV Wang, Y Xia - Annals of biomedical engineering, 2016 - Springer
At the intersection of life sciences, materials science, engineering, and medicine,
regenerative medicine stands out as a rapidly progressing field that aims at retaining …

Breakthroughs in photonics 2013: photoacoustic tomography in biomedicine

J Yao, LV Wang - IEEE photonics journal, 2014 - ieeexplore.ieee.org
Photoacoustic tomography (PAT) is one of the fastest growing biomedical imaging
modalities in the last decade. Building on its high scalability and complementary imaging …

Challenging a preconception: Optoacoustic spectrum differs from the absorption spectrum of proteins and dyes for molecular imaging

JPF Werner, Y Huang, K Mishra, R Janowski… - BioRxiv, 2020 - biorxiv.org
Optoacoustic (photoacoustic) imaging has seen marked technological advances in detection
and data analysis, but there is less progress in understanding the photophysics of …

Short and long-term phototoxicity in cells expressing genetic reporters under nanosecond laser exposure

S Gottschalk, H Estrada, O Degtyaruk, J Rebling… - Biomaterials, 2015 - Elsevier
Nanosecond-duration laser pulses are exploited in a plethora of therapeutic and diagnostic
applications, such as optoacoustic imaging. However, phototoxicity effects of pulsed …

[HTML][HTML] In vitro optoacoustic flow cytometry with light scattering referencing

M Seeger, AC Stiel, V Ntziachristos - Scientific Reports, 2021 - nature.com
Morphological and functional optoacoustic imaging is enhanced by dedicated transgene
reporters, in analogy to fluorescence methods. The development of optoacoustic reporters …

Lifetime-weighted photoacoustic imaging

A Forbrich, P Shao, W Shi, RJ Zemp - Journal of Optics, 2016 - iopscience.iop.org
Photoacoustic (PA) imaging has been utilized to quantify the lifetime profile of exogenous
agents using a series of pump-probe pulses with a varying time delay; however, current …