HIV‐Related Immune Activation and Inflammation: Current Understanding and Strategies
T Lv, W Cao, T Li - Journal of immunology research, 2021 - Wiley Online Library
Although antiretroviral therapy effectively controls human immunodeficiency virus (HIV)
replication, a residual chronic immune activation/inflammation persists throughout the …
replication, a residual chronic immune activation/inflammation persists throughout the …
Microbial infections are a risk factor for neurodegenerative diseases
SK Lotz, BM Blackhurst, KL Reagin… - Frontiers in Cellular …, 2021 - frontiersin.org
Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and
amyotrophic lateral sclerosis, comprise a family of disorders characterized by progressive …
amyotrophic lateral sclerosis, comprise a family of disorders characterized by progressive …
Bio-indicators in cadmium toxicity: Role of HSP27 and HSP70
ME Taghavizadeh Yazdi, MS Amiri… - … Science and Pollution …, 2021 - Springer
Heat shock proteins (HSPs) are a family of proteins that are expressed by cells in reply to
stressors. The changes in concentration of HSPs could be utilized as a bio-indicator of …
stressors. The changes in concentration of HSPs could be utilized as a bio-indicator of …
Cadmium-induced IL-6 and IL-8 expression and release from astrocytes are mediated by MAPK and NF-κB pathways
S Phuagkhaopong, D Ospondpant, T Kasemsuk… - Neurotoxicology, 2017 - Elsevier
Chronic exposure to cadmium has been linked to brain cancers, learning disabilities and
memory deficits. Previous studies of cadmium toxicity in the central nervous system report …
memory deficits. Previous studies of cadmium toxicity in the central nervous system report …
HIV-associated neurotoxicity and cognitive decline: Therapeutic implications
DR Wallace - Pharmacology & Therapeutics, 2022 - Elsevier
As our understanding of changes to the neurological system has improved, it has become
clear that patients who have contracted human immunodeficiency virus type 1 (HIV-1) can …
clear that patients who have contracted human immunodeficiency virus type 1 (HIV-1) can …
Roles of Interleukin-6-mediated immunometabolic reprogramming in COVID-19 and other viral infection-associated diseases
YS Li, HC Ren, JH Cao - International Immunopharmacology, 2022 - Elsevier
Abstract Interleukin-6 (IL-6) is a highly pleiotropic glycoprotein factor that can modulate
innate and adaptive immunity as well as various aspects of metabolism, including glycolysis …
innate and adaptive immunity as well as various aspects of metabolism, including glycolysis …
Functional impact of HIV-1 Tat on cells of the CNS and its role in HAND
J Marino, ME Maubert, AR Mele, C Spector… - Cellular and Molecular …, 2020 - Springer
Human immunodeficiency virus type 1 (HIV-1) transactivator of transcription (Tat) is a potent
mediator involved in the development of HIV-1-associated neurocognitive disorders …
mediator involved in the development of HIV-1-associated neurocognitive disorders …
Does HIV infection contribute to increased beta-amyloid synthesis and plaque formation leading to neurodegeneration and Alzheimer's disease?
HIV infection in the combination antiretroviral therapy (cART) era has become a chronic
disease with a life expectancy almost identical to those free from this infection …
disease with a life expectancy almost identical to those free from this infection …
Humanized mice for studies of HIV-1 persistence and elimination
A major roadblock to achieving a cure for human immunodeficiency virus type one (HIV-1) is
the persistence of latent viral infections in the cells and tissue compartments of an infected …
the persistence of latent viral infections in the cells and tissue compartments of an infected …
Targeting infectious agents as a therapeutic strategy in Alzheimer's disease
Alzheimer's disease (AD) is the most prevalent dementia in the world. Its cause (s) are
presently largely unknown. The most common explanation for AD, now, is the amyloid …
presently largely unknown. The most common explanation for AD, now, is the amyloid …