Aminolevulinic acid (ALA) is an endogenous metabolite normally formed in the mitochondria
from succinyl-CoA and glycine. Conjugation of eight ALA molecules yields protoporphyrin IX …

Abstract Heme oxygenase-1 (HO-1) catalyzes heme degradation to generate biliverdin-IXα,
carbon monoxide (CO), and iron. The HO-1/CO system confers cytoprotection in animal …

In photodynamic therapy (PDT) a sensitizer, light and oxygen are used to induce death of
tumor cells and in the treatment of certain noncancerous conditions. Cell death in PDT may …

Accumulation of heme oxygenase mRNA is strongly stimulated by treatment of cultured
human skin fibroblasts with ultraviolet radiation, hydrogen peroxide, or the sulfhydryl reagent …

Heme oxygenase-1 (HO-1) catalyzes the oxidation of heme to biologically active products:
carbon monoxide (CO), biliverdin, and ferrous iron. It participates in maintaining cellular …

Citation Soleymaninejadian E, Pramanik K, Samadian E. Immunomodulatory properties of
mesenchymal stem cells: cytokines and factors. Am J Reprod Immunol 2012; 67: 1–8 …

Resveratrol (3, 4′, 5-trihydroxy stilbene), a phytoalexin found in the skin and seeds of
grapes, has been reported to possess anti-inflammatory, anticarcinogenic, and antioxidant …

Reactive oxygen species (ROS) can be both beneficial and deleterious. Under normal
physiological conditions, ROS production is tightly regulated, and ROS participate in both …

Abstract Haem oxygenase-1 (HO1) is a heat-shock protein that is induced by stressful
stimuli. Here we demonstrate a cytoprotective role for HO1: cell death produced by serum …

Non-alcoholic fatty liver disease (NAFLD) is an emerging metabolic-related disorder
characterized by fatty infiltration of the liver in the absence of alcohol consumption. NAFLD …