Due to the fact that mRNA technology allows the production of diverse vaccines and
treatments in a shorter time frame and with reduced expense compared to conventional …

Transition metal elements, such as copper, play diverse and pivotal roles in oncology. They
act as constituents of metalloenzymes involved in cellular metabolism, function as signaling …

The dense stroma of desmoplastic tumor limits nanotherapeutic penetration and hampers
the antitumor immune response. Here, we report a denaturation-and-penetration strategy …

Gene therapy provides a promising approach in treating cancers with high efficacy and
selectivity and few adverse effects. Currently, the development of functional vectors with …

Tumor‐associated macrophages (TAMs) play a critical role in the immunosuppressive solid
tumor microenvironment (TME), yet in situ engineering of TAMs for enhanced tumor …

Messenger RNA (mRNA)–based therapeutics are transforming the landscapes of medicine,
yet targeted delivery of mRNA to specific cell types while minimizing off-target accumulation …

Upon entering the biological milieu, nanomedicines swiftly interact with the surrounding
tissue fluid, subsequently being enveloped by a dynamic interplay of biomacromolecules …

Compared to injection administration, oral administration is free of discomfort, wound
infection, and complications and has a higher compliance rate for patients with diverse …

Incomplete microwave ablation (iMWA) caused by uncontrollable heat diffusion enhances
the immunosuppressive tumor microenvironment (ITM), consequently disabling the …

Immunotherapy as an alternative treatment strategy for B-cell lymphoma is undesirable
because of tumor heterogeneity and immune surveillance. Spermidine (SPM), as a regulator …