Aβ-oligomers: A potential therapeutic target for Alzheimer's disease
The cascade of amyloid formation relates to multiple complex events at the molecular level.
Previous research has established amyloid plaque deposition as the leading cause of …
Previous research has established amyloid plaque deposition as the leading cause of …
Microglial activation and priming in Alzheimer's disease: state of the art and future perspectives
Alzheimer's Disease (AD) is the most common cause of dementia, having a remarkable
social and healthcare burden worldwide. Amyloid β (Aβ) and protein Tau aggregates are …
social and healthcare burden worldwide. Amyloid β (Aβ) and protein Tau aggregates are …
Therapeutic strategies aimed at improving neuroplasticity in Alzheimer disease
MF Colavitta, FJ Barrantes - Pharmaceutics, 2023 - mdpi.com
Alzheimer disease (AD) is the most prevalent form of dementia among elderly people.
Owing to its varied and multicausal etiopathology, intervention strategies have been highly …
Owing to its varied and multicausal etiopathology, intervention strategies have been highly …
CX3CL1 pathway as a molecular target for treatment strategies in Alzheimer's disease
G Bivona, M Iemmolo, G Ghersi - International Journal of Molecular …, 2023 - mdpi.com
Alzheimer's disease (AD) is a scourge for patients, caregivers and healthcare professionals
due to the progressive character of the disease and the lack of effective treatments. AD is …
due to the progressive character of the disease and the lack of effective treatments. AD is …
[HTML][HTML] Unveiling the molecular Footprint: Proteome-based biomarkers for Alzheimer's disease
Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by
progressive cognitive decline and memory loss. Early and accurate diagnosis of AD is …
progressive cognitive decline and memory loss. Early and accurate diagnosis of AD is …
Realization of amyloid-like aggregation as a common cause for pathogenesis in diseases
S Naskar, N Gour - Life, 2023 - mdpi.com
Amyloids were conventionally referred to as extracellular and intracellular accumulation of
Aβ42 peptide, which causes the formation of plaques and neurofibrillary tangles inside the …
Aβ42 peptide, which causes the formation of plaques and neurofibrillary tangles inside the …
Exploring Advancements in Early Detection of Alzheimer's Disease with Molecular Assays and Animal Models
Alzheimer's Disease (AD) is a challenging neurodegenerative condition, with overwhelming
implications for affected individuals and healthcare systems worldwide. Animal models have …
implications for affected individuals and healthcare systems worldwide. Animal models have …
Neuroprotective and anti‐inflammatory effects of curcumin in Alzheimer's disease: Targeting neuroinflammation strategies
E Azzini, SI Peña‐Corona… - Phytotherapy …, 2024 - Wiley Online Library
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by the
accumulation of amyloid‐beta plaques and neurofibrillary tangles, leading to neuronal loss …
accumulation of amyloid‐beta plaques and neurofibrillary tangles, leading to neuronal loss …
MRI‐based axis‐referenced morphometric model corresponding to lamellar organization for assessing hippocampal atrophy in dementia
Research on the local hippocampal atrophy for early detection of dementia has gained
considerable attention. However, accurately quantifying subtle atrophy remains challenging …
considerable attention. However, accurately quantifying subtle atrophy remains challenging …