Apoptosis or programmed cell death is natural way of removing aged cells from the body.
Most of the anti-cancer therapies trigger apoptosis induction and related cell death networks …

Gossypol is a phenolic compound produced by pigment glands in cotton stems, leaves,
seeds, and flower buds (Gossypium spp.). Cottonseed meal is a by‐product of cotton that is …

Overexpression of members of the BCL-2 family of pro-survival proteins is commonly
associated with unfavourable pathogenesis in cancer. The convergence of cytotoxic stress …

Glioblastoma multiforme (GBM) is the most common primary brain tumour in adults and one
of the most aggressive cancers in man. Despite technological advances in surgical …

Plants have been used as a source of medicine throughout history and continue to serve as
the basis for many pharmaceuticals used today. Although the modern pharmaceutical …

Covering up to 2022 Gossypol is a polyphenolic compound isolated from cottonseed. There
are two optical enantiomers of gossypol,(−)-gossypol and (+)-gossypol. Gossypol exists as …

In many different species, lactate dehydrogenase (LDH) constitutes a major checkpoint of
anaerobic glycolysis, by catalyzing the reduction of pyruvate into lactate. This enzyme has …

Cancer metastasis to distant organs is initiated by tumor cells that disseminate from primary
heterogeneous tumors. The subsequent growth and survival of tumor metastases depend on …

Background Cottonseed meal (CSM) is the main by-product of the cottonseed oil extraction
process with high protein content, which is an important protein source for feed industry …

There is growing acceptance of traditional Chinese medicines (TCMs) as potential sources
of clinical agents based on the demonstrated efficacies of numerous bioactive compounds …