A series of aromatic gossypol Schiff bases have been successfully synthesized via a
feasible chemical modification. The antiviral activity against tobacco mosaic virus (TMV) of …

The latest findings on the role played by human LDH5 (h LDH5) in the promotion of
glycolysis in invasive tumor cells indicates that this enzyme subtype is a promising …

Background Hormesis is a biphasic biological response characterized by the stimulatory
effect at relatively low amounts of chemical compounds which are otherwise detrimental at …

Several recent insights into the roles of mitochondria in cancer have renewed efforts to
develop nongenotoxic therapies targeting mitochondrial proteins and functions …

Gossypol is a polyphenolic secondary metabolite produced by cotton plants, which is toxic to
many organisms. Gossypol's aldehyde groups are especially reactive, forming Schiff bases …

Background Phyto-remedies for diabetic control are popular among patients with Type II
Diabetes mellitus (DM), in addition to other diabetic control measures. A number of plant …

Gossypol is a part of the cotton plant's defense system against pathogens and herbivorous
insects. To discover gossypol analogs with broad spectrum and high activity, a series of …

Prostate cancer continues to represent a burgeoning medical problem in the United States.
Recent studies suggest that gossypol, a bioactive phytochemical produced by cotton plants …

Abstract Uridine diphosphate (UDP)-glycosyltransferases (UGTs) catalyze the addition of
UDP-sugars to small hydrophobic molecules, turning them into more water-soluble …

Abstract Ethnopharmacological relevance The Malvaceae family, an important group of
plants that have the Gossypium (cotton) genus has been used in folk medicine to treat …