Pre-clinical and clinical implications of “inside-out” vs.“outside-in” paradigms in multiple sclerosis etiopathogenesis

HE Titus, Y Chen, JR Podojil, AP Robinson… - Frontiers in cellular …, 2020 - frontiersin.org
Multiple Sclerosis (MS) is an immune-mediated neurological disorder, characterized by
central nervous system (CNS) inflammation, oligodendrocyte loss, demyelination, and …

Military-related mild traumatic brain injury: clinical characteristics, advanced neuroimaging, and molecular mechanisms

SY Kim, PH Yeh, JM Ollinger, HD Morris… - Translational …, 2023 - nature.com
Mild traumatic brain injury (mTBI) is a significant health burden among military service
members. Although mTBI was once considered relatively benign compared to more severe …

[HTML][HTML] White matter microstructure across the adult lifespan: A mixed longitudinal and cross-sectional study using advanced diffusion models and brain-age …

D Beck, AMG de Lange, II Maximov, G Richard… - NeuroImage, 2021 - Elsevier
The macro-and microstructural architecture of human brain white matter undergoes
substantial alterations throughout development and ageing. Most of our understanding of …

Experimental traumatic brain injury identifies distinct early and late phase axonal conduction deficits of white matter pathophysiology, and reveals intervening recovery

CM Marion, KL Radomski, NP Cramer… - Journal of …, 2018 - Soc Neuroscience
Traumatic brain injury (TBI) patients often exhibit slowed information processing speed that
can underlie diverse symptoms. Processing speed depends on neural circuit function at …

Sarm1 deletion reduces axon damage, demyelination, and white matter atrophy after experimental traumatic brain injury

CM Marion, DP McDaniel, RC Armstrong - Experimental neurology, 2019 - Elsevier
Traumatic brain injury (TBI) often damages axons in white matter tracts and causes corpus
callosum (CC) atrophy in chronic TBI patients. Injured axons encounter irreversible damage …

Diffusion-weighted imaging in mild traumatic brain injury: a systematic review of the literature

HM Lindsey, CB Hodges, KM Greer, EA Wilde… - Neuropsychology …, 2023 - Springer
There is evidence that diffusion-weighted imaging (DWI) is able to detect tissue alterations
following mild traumatic brain injury (mTBI) that may not be observed on conventional …

Beyond diffusion tensor MRI methods for improved characterization of the brain after ischemic stroke: a review

EVR DiBella, A Sharma, L Richards… - American Journal …, 2022 - Am Soc Neuroradiology
Ischemic stroke is a worldwide problem, with 15 million people experiencing a stroke
annually. MR imaging is a valuable tool for understanding and assessing brain changes …

The impact of exercise, sleep, and diet on neurocognitive recovery from mild traumatic brain injury in older adults: A narrative review

SJ Markovic, M Fitzgerald, JJ Peiffer, BR Scott… - Ageing research …, 2021 - Elsevier
Mild traumatic brain injury (mTBI) accounts for a large majority of traumatic brain injuries
sustained globally each year. Older adults, who are already susceptible to age-related …

Neuroprotective effect of lithium in cold-induced traumatic brain injury in mice

E Ciftci, R Karaçay, A Caglayan, S Altunay… - Behavioural brain …, 2020 - Elsevier
Apart from its well-established therapeutic activity on bipolar disorder and depression,
lithium exerts neuroprotective activity upon neurodegenerative disorders, such as traumatic …

Intracameral injection of a chemically cross-linked hydrogel to study chronic neurodegeneration in glaucoma

KC Chan, Y Yu, SH Ng, HK Mak, YWY Yip… - Acta biomaterialia, 2019 - Elsevier
Investigation of neurodegeneration in glaucoma, a leading cause of irreversible blindness
worldwide, has been obfuscated by the lack of an efficient model that provides chronic, mild …