The past 20 years have witnessed ever-growing evidence that the mechanical properties of
biological tissues, from nanoscale to macroscale dimensions, are fundamental for cellular …

The novel coronavirus (SARS‐CoV‐2) has turned into a life‐threatening pandemic disease
(Covid‐19). About 5% of patients with Covid‐19 have severe symptoms including septic …

The role of N 6-methyladenosine (m6A) modifications in renal diseases is largely unknown.
Here, we characterized the role of N 6-adenosine-methyltransferase-like 3 (METTL3), whose …

It is unclear whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can
directly infect human kidney, thus leading to acute kidney injury (AKI). Here, we perform a …

Chronic kidney disease (CKD) is a devastating condition that is reaching epidemic levels
owing to the increasing prevalence of diabetes mellitus, hypertension and obesity, as well …

Chronic kidney disease (CKD) is a chronic renal dysfunction syndrome that is characterized
by nephron loss, inflammation, myofibroblasts activation, and extracellular matrix (ECM) …

Fibrosis is defined as an excessive deposition of connective tissue components and can
affect virtually every organ system, including the skin, lungs, liver and kidney. Fibrotic tissue …

Transforming growth factor-β1 (TGF-β1) is considered as a crucial mediator in tissue fibrosis
and causes tissue scarring largely by activating its downstream small mother against …

Increasing evidence suggests that renal inflammation contributes to the pathogenesis and
progression of diabetic kidney disease (DKD) and that anti-inflammatory therapies might …

Despite recent advances in the management of chronic kidney disease (CKD), morbidity
and mortality rates in these patients remain high. While pressure-mediated injury is a well …