Reshaping the transcriptional frontier: epigenetics and somatic cell nuclear transfer

CR Long, ME Westhusin… - Molecular reproduction …, 2014 - Wiley Online Library
Somatic‐cell nuclear transfer (SCNT) experiments have paved the way to the field of cellular
reprogramming. The demonstrated ability to clone over 20 different species to date has …

Molecular mechanisms regulating spermatogenesis in vertebrates: Environmental, metabolic, and epigenetic factor effects

B Guerra-Carvalho, DF Carrageta, L Crisóstomo… - Animal Reproduction …, 2022 - Elsevier
The renewal of the natural resources is one of the most concerning aspects of modern
farming. In animal production, there are many barriers breeders and researchers have to …

Full-term development of gaur–bovine interspecies somatic cell nuclear transfer embryos: effect of trichostatin A treatment

K Srirattana, S Imsoonthornruksa… - … " Cloning and Stem …, 2012 - liebertpub.com
Trichostatin A (TSA) has previously been used in somatic cell nuclear transfer (SCNT) to
improve the cloning efficiency in several species, which led our team to investigate the …

Development to term of cloned cattle derived from donor cells treated with valproic acid

JR Sangalli, MR Chiaratti, THC De Bem… - PLoS …, 2014 - journals.plos.org
Cloning of mammals by somatic cell nuclear transfer (SCNT) is still plagued by low
efficiency. The epigenetic modifications established during cellular differentiation are a …

Recent progress in bovine somatic cell nuclear transfer

S Akagi, M Geshi, T Nagai - Animal science journal, 2013 - Wiley Online Library
Bovine somatic cell nuclear transfer (SCNT) embryos can develop to the blastocyst stage at
a rate similar to that of embryos produced by in vitro fertilization. However, the full‐term …

Treatment of donor cells and reconstructed embryos with a combination of trichostatin-A and 5-aza-2′-deoxycytidine improves the developmental competence and …

M Saini, NL Selokar, H Agrawal, SK Singla… - Cellular …, 2017 - liebertpub.com
The application of cloning technology on a large scale is limited by very low offspring rate
primarily due to aberrant or incomplete epigenetic reprogramming. Trichostatin A (TSA), a …

Effects of intravenous infusion with sodium butyrate on colonic microbiota, intestinal development-and mucosal immune-related gene expression in normal growing …

X Chen, J Xu, Y Su, W Zhu - Frontiers in Microbiology, 2018 - frontiersin.org
This study aimed to investigate effects of intravenous infusion with sodium butyrate (SB) on
colonic microbiota, intestinal mucosal immune and intestinal development in normal …

Treatment of nuclear-donor cells or cloned zygotes with chromatin-modifying agents increases histone acetylation but does not improve full-term development of …

JR Sangalli, THC De Bem, F Perecin… - … " Cloning and Stem …, 2012 - liebertpub.com
Although somatic cell nuclear transfer (SCNT) is a promising tool, its potential use is
hampered by the high mortality rates during the development to term of cloned offspring …

On chip electrofusion of single human B cells and mouse myeloma cells for efficient hybridoma generation

EWM Kemna, F Wolbers, I Vermes… - …, 2011 - Wiley Online Library
This article describes the development and full characterization of a microfluidic chip for
electrofusion of human peripheral blood B‐cells and mouse myeloma (NS‐1) cells to …

Effect of Additional Cytoplasm of Cloned Embryo on In Vitro Developmental Competence and Reprogramming Efficiency in Mice

SH Song, SH Oh, L Xu, KL Lee, JY Hwang… - Cellular …, 2020 - liebertpub.com
Somatic cell nuclear transfer (SCNT) is an important technique for biological science
research. Cytoplasm injection cloning technology (CICT) was developed to improve the …