Although the signal transducer and activator of transcription (STAT) proteins were originally
discovered through the study of interferon-induced responses, a large number of cytokines …

Viruses commonly antagonize the antiviral type I interferon response by targeting signal
transducer and activator of transcription 1 (STAT1) and STAT2, key mediators of interferon …

Viral infections are known to hijack the transcription and translation of the host cell.
However, the extent to which viral proteins coordinate these perturbations remains unclear …

Human T-lymphotropic virus type 1 (HTLV-1) is linked to multiple diseases, including the
neuroinflammatory disease HTLV-1–associated myelopathy/tropical spastic paraparesis …

Adult T cell leukemia is an aggressive and frequently fatal malignancy that expressess
constitutively activated growth-signaling pathways in association with deregulated growth …

Human T-lymphotropic virus type 1 (HTLV-1) infection is associated with the clonal
expansion and transformation of mature T lymphocytes. While the mechanisms involved are …

The cancer preventive action of (−)‐epigallocatechin gallate (EGCG), found in green tea, is
strongly supported by epidemiology and laboratory research data. However, the mechanism …

The retroviral oncoprotein Tax from human T-cell leukemia virus type 1 (HTLV-1), an
etiological factor that causes adult T-cell leukemia and lymphoma, has a crucial role in …

Having co-evolved with humans, herpesviruses have adapted to exploit the host molecular
machinery to ensure viral persistence. The cellular protein Signal Transducer and Activator …

Infection of the brain by lentiviruses, including human immunodeficiency virus (HIV) and
feline immunodeficiency virus (FIV), causes inflammation and results in neurodegeneration …