[HTML][HTML] Applications of nanotechnologies for miRNA-based cancer therapeutics: Current advances and future perspectives

LA Bravo-Vázquez, A Méndez-García… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Abstract MicroRNAs (miRNAs) are short (18–25 nt), non-coding, widely conserved RNA
molecules responsible for regulating gene expression via sequence-specific post …

Polymeric dendrimers as nanocarrier vectors for neurotheranostics

H Li, S Zha, H Li, H Liu, KL Wong, AH All - Small, 2022 - Wiley Online Library
Dendrimers are polymers with well‐defined 3D branched structures that are vastly utilized in
various neurotheranostics and biomedical applications, particularly as nanocarrier vectors …

[HTML][HTML] HOXA1 participates in VSMC-to-macrophage-like cell transformation via regulation of NF-κB p65 and KLF4: a potential mechanism of atherosclerosis …

Z Han, H Hu, MZ Yin, Y Lin, Y Yan, P Han, B Liu… - Molecular …, 2023 - Springer
Background Macrophage-like transformation of vascular smooth muscle cells (VSMCs) is a
risk factor of atherosclerosis (AS) progression. Transcription factor homeobox A1 (HOXA1) …

Non-coding RNA-based therapeutics in cancer therapy: An emphasis on Wnt/β-catenin control

A Taheriazam, SD Bayanzadeh, MH Farahani… - European Journal of …, 2023 - Elsevier
Non-coding RNA transcripts are RNA molecules that have mainly regulatory functions and
they do not encode proteins. microRNAs (miRNAs), lncRNAs and circRNAs are major types …

[HTML][HTML] Role of nano-mirnas in diagnostics and therapeutics

D Coradduzza, E Bellu, A Congiargiu… - International Journal of …, 2022 - mdpi.com
MicroRNAs (miRNA) are key regulators of gene expression, controlling different biological
processes such as cellular development, differentiation, proliferation, metabolism, and …

[HTML][HTML] The important role of miR-1-3p in cancers

S Dai, F Li, S Xu, J Hu, L Gao - Journal of Translational Medicine, 2023 - Springer
Cancer is a malignant tumor that seriously threatens human life and health. At present, the
main treatment methods include surgical resection, chemotherapy, radiotherapy, and …

MicroRNA therapeutic delivery strategies: A review

H Tian, L Cheng, Y Liang, H Lei, M Qin, X Li… - Journal of Drug Delivery …, 2024 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs containing 18–25 nucleotides. They exist
widely in animals, plants and pathogenic microorganisms. At present, more than 1900 …

[HTML][HTML] Preparation and Optimization of MiR-375 Nano-Vector Using Two Novel Chitosan-Coated Nano-Structured Lipid Carriers as Gene Therapy for Hepatocellular …

B Soliman, MM Wen, E Kandil, B El-Agamy… - Pharmaceutics, 2024 - mdpi.com
Currently, there is still a lack of effective carriers with minimal side effects to deliver
therapeutic miRNA. Thus, it is crucial to optimize novel drug delivery systems. MiR-375 has …

[HTML][HTML] Role of HOXA1-4 in the development of genetic and malignant diseases

L Wang, H Sun, L Cao, J Wang - Biomarker Research, 2024 - Springer
The HOXA genes, belonging to the HOX family, encompass 11 members (HOXA1-11) and
exert critical functions in early embryonic development, as well as various adult processes …

[HTML][HTML] In Silico and In Vivo Evaluation of microRNA-181c-5p's Role in Hepatocellular Carcinoma

ON Abd ElAziz, AM Elfiky, MA Yassin… - Genes, 2022 - mdpi.com
Hepatocellular carcinoma (HCC) is a fatal disease, accounting for 75–85% of primary liver
cancers. The conclusive research on miR-181c-5p's role in hepatocarcinogenesis, whether …