Neural tube defects (NTDs) are the second most common congenital malformations in
humans affecting the development of the central nervous system. Although NTD …

Background Pre-gestational diabetes mellitus (PGDM) has been known to be a risk factor for
congenital heart defects (CHDs) for decades. However, the associations between maternal …

OBJECTIVE To examine the association of maternal prepregnancy diabetes, gestational
diabetes mellitus (GDM), and 12 subtypes of congenital anomalies of the newborn …

Context Evidence suggests an association between maternal obesity and some congenital
anomalies. Objective To assess current evidence of the association between maternal …

Reports on the gestational diabetes mellitus (GDM) recurrence rate have been highly
variable. Our objectives were to examine the possible causes of GDM recurrence rate …

We conducted a metaanalysis of published evidence on the relationship between maternal
obesity and the risk of neural tube defects (NTDs). Eligible studies were identified from 3 …

Objective To describe the relation between maternal obesity, overweight and underweight
status, and 16 categories of structural birth defects. Design An ongoing multisite, case …

Background The risk of birth defects after antenatal exposure to selective serotonin-reuptake
inhibitors (SSRIs) remains controversial. Methods We assessed associations between first …

Estimates of the lifetime risk of major depression in women range from 10% to 25%, peaking
during the reproductive years. Today, selective serotonin-reuptake inhibitors (SSRIs) are the …

Objective To review the evidence and provide recommendations for the counselling and
management of obese parturients. Outcomes Outcomes evaluated include the impact of …