Mitochondria are not only the main energy supplier but are also the cell metabolic center
regulating multiple key metaborates that play pivotal roles in epigenetics regulation. These …

The role of malate dehydrogenase (MDH) in the metabolism of various medically significant
protozoan parasites is reviewed. MDH is an NADH-dependent oxidoreductase that …

Schistosomiasis is a parasitic disease that afflicts approximately 250 million people
worldwide. There is an urgent demand for new antiparasitic agents because praziquantel …

Plasmodium vivax is the most widespread cause of malaria, especially in subtropical and
temperate regions such as Asia-Pacific and America. P. vivax lactate dehydrogenase …

This study developed a class of novel structural antifungal hydrazylnaphthalimidols (HNs)
with multitargeting broad-spectrum potential via multicomponent hybridization to confront …

Lactate dehydrogenase (LDH, EC 1.1. 1.27) is one of the vital glycolytic conditions,
especially during anaerobic conditions. It is a significant diagnostic, prognostic, and …

Vaccines are among the most important advances in medicine throughout the human
history. However, conventional vaccines exhibit several drawbacks in terms of design and …

Ethnopharmacological relevance Parasitic infections impose a significant burden on public
health worldwide. European pharmacopoeia records and ethnopharmacological studies …

Cellular metabolism comprises a complex network of biochemical anabolic and catabolic
processes that fuel the growth and survival of living organisms. The enzyme malate …

Plasmodium falciparum is the pathogen responsible for 90% of all malaria cases and is
associated with severe complications and the highest fatality rate. Plasmodium falciparum …