Purpose: To review and summarize the syndromic, nonsyndromic, and systemic
associations of congenital lacrimal drainage anomalies. Methods: The authors performed a …

The understanding of lacrimal embryology is very crucial to the understanding of lacrimal
anatomy and its subsequent clinical and surgical applications. In addition, numerous …

Congenital nasolacrimal duct obstruction (CNLDO) is a common cause of epiphora in
children. Management of CNLDO is principally guided by natural history of disease and high …

We produced a tear proteome of the genome mouse, C57BL/6, that contained 139 different
protein identifications: 110 from a two-dimensional (2D) gel with subsequent trypsin …

Abstract Objectives Koolen–de Vries Syndrome (KdVS) is a rare multisystem
neurodevelopmental disorder. Ocular manifestations, including strabismus, ptosis, and …

Purpose: To investigate whether patients with craniosynostosis exhibit higher rates of
nasolacrimal duct obstruction (NLDO) and to explore potential risk factors. Methods …

Aplasia/agenesis of lacrimal and salivary glands is a rare congenital defect that has been
associated with disturbances in fibroblast growth factor 10 (FGF10). It can present with …

Congenital dacryostenosis is the most common reason for ophthalmic consultation in
childhood. It is most often caused by persisting of Hasnerʼs membrane. However …

Purpose: Obstruction of the tear drainage causes a range of ocular surface disorders.
Hitherto, the genetics of tear duct development and obstruction has been scarcely explored …

Congenital alacrima is an uncommon condition marked by a lack of tear production that is
present from birth. This condition often occurs in conjunction with various syndromes but can …