Peripheral immune function and Alzheimer's disease: a living systematic review and critical appraisal
Background A growing body of literature examines the relationship between peripheral
immune function and Alzheimer's Disease (AD) in human populations. Our living systematic …
immune function and Alzheimer's Disease (AD) in human populations. Our living systematic …
Circulating biomarkers of inflammaging and Alzheimer's disease to track age-related trajectories of dementia: Can we develop a clinically relevant composite …
AM Abbatecola, A Giuliani, L Biscetti, L Scisciola… - Ageing Research …, 2024 - Elsevier
Alzheimer's disease (AD) is a rapidly growing global concern due to a consistent rise of the
prevalence of dementia which is mainly caused by the aging population worldwide. An early …
prevalence of dementia which is mainly caused by the aging population worldwide. An early …
CSF biomarkers of immune activation and Alzheimer's disease for predicting cognitive impairment risk in the elderly
The immune system substantially influences age-related cognitive decline and Alzheimer's
disease (AD) progression, affected by genetic and environmental factors. In a Mayo Clinic …
disease (AD) progression, affected by genetic and environmental factors. In a Mayo Clinic …
Association of peripheral B cells and delirium: combined single-cell sequencing and Mendelian randomization analysis
S Tan, S Pan, L Wei, W Chen, B Pan, G Kong… - Frontiers in …, 2024 - frontiersin.org
Background Delirium seriously affects the prognosis of patients and greatly reduces the
ability to work and live. Peripheral inflammatory events may contribute to the development of …
ability to work and live. Peripheral inflammatory events may contribute to the development of …
[HTML][HTML] Research progress in Alzheimer's disease and bone-brain axis
F Zhang, W Zhang - Ageing Research Reviews, 2024 - Elsevier
Alzheimer's disease (AD) is the most common type of cognitive impairment. AD is closely
related to orthopedic diseases, such as osteoporosis and osteoarthritis, in terms of …
related to orthopedic diseases, such as osteoporosis and osteoarthritis, in terms of …
Blood‐based inflammatory protein biomarker panel for the prediction of relapse and severity in patients with neuromyelitis optica spectrum disorder: A prospective …
Q Wei, J Li, C Zhao, S Meng, N Liu, Z Wu… - CNS Neuroscience …, 2024 - Wiley Online Library
Background To date, most existing models for predicting neuromyelitis optica spectrum
disorder (NMOSD) are based primarily on clinical characteristics. Blood‐based NMOSD …
disorder (NMOSD) are based primarily on clinical characteristics. Blood‐based NMOSD …
Methods and clinical biomarker discovery for targeted proteomics using Olink technology
H Wang, T Zhao, J Zeng, R Zhang, L Pu… - PROTEOMICS …, 2024 - Wiley Online Library
Purpose This paper is to offer insights for designing research utilizing Olink technology to
identify biomarkers and potential therapeutic targets for disease treatment. Experimental …
identify biomarkers and potential therapeutic targets for disease treatment. Experimental …
[HTML][HTML] Proteome-wide association studies using summary proteomic data identified 23 risk genes of Alzheimer's disease
Characterizing the genetic mechanisms underlying Alzheimer's disease (AD) dementia is
crucial for developing new therapeutics. Proteome-wide association study (PWAS) …
crucial for developing new therapeutics. Proteome-wide association study (PWAS) …
Circulating inflammatory proteins may be potential drug targets for Idiopathic Membranous Nephropathy: proteome-wide Mendelian Randomization and colocalization …
Z Su, Q Rao, D Wu, Z Yin, W Liu, Q Wan - medRxiv, 2023 - medrxiv.org
Background: Idiopathic membranous nephropathy (IMN) is a predominant cause of
nephrotic syndrome among adults. Existing drugs are ineffective in about one-third of IMN …
nephrotic syndrome among adults. Existing drugs are ineffective in about one-third of IMN …
[HTML][HTML] Aging-Related Immune Cell Phenotypes and Mortality in the Framingham Heart Study
Background The global increase in human life expectancy is evident. The total number of
individuals aged 60 or above is anticipated to reach 2 billion by 2050. Aging, an inherently …
individuals aged 60 or above is anticipated to reach 2 billion by 2050. Aging, an inherently …