The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …

Dentine hypersensitivity is a common oral pain condition affecting many individuals. The
aetiology is multifactorial; however, over recent years the importance of erosion has become …

Peripheral detection of nociceptive and painful stimuli by sensory neurons involves a
complex repertoire of molecular detectors and/or transducers on distinct subsets of nerve …

Specialized receptors belonging to the transient receptor potential (TRP) family of ligand-
gated ion channels constitute the critical detectors and transducers of pain-causing stimuli …

Dental pain is a common health problem that negatively impacts the activities of daily living.
Dentine hypersensitivity and pulpitis-associated pain are among the most common types of …

Due, in part, to the unique structure of the tooth, dental pain is initiated via distinct
mechanisms. Here we review recent advances in our understanding of inflammatory tooth …

Odontoblasts are the dental pulp cells responsible for the formation of dentin. In addition,
accumulating data strongly suggest that they can also function as sensory cells that mediate …

The tooth has an unusual sensory system that converts external stimuli predominantly into
pain, yet its sensory afferents in teeth demonstrate cytochemical properties of non …

Eugenol is a bioactive plant extract used as an analgesic agent in dentistry. The structural
similarity of eugenol to cinnamaldehyde, an active ligand for transient receptor potential …

Aim To assess the effects of central administration of α‐pinene alone and in combination
with either bicuculline or naloxone, as GABA A and μ‐opioid receptor antagonists …