Benefits of metformin in attenuating the hallmarks of aging

AS Kulkarni, S Gubbi, N Barzilai - Cell metabolism, 2020 - cell.com
Biological aging involves an interplay of conserved and targetable molecular mechanisms,
summarized as the hallmarks of aging. Metformin, a biguanide that combats age-related …

Gestational diabetes mellitus

HD McIntyre, P Catalano, C Zhang, G Desoye… - Nature reviews Disease …, 2019 - nature.com
Hyperglycaemia that develops during pregnancy and resolves after birth has been
recognized for over 50 years, but uniform worldwide consensus is lacking about threshold …

Tirzepatide once weekly for the treatment of obesity

AM Jastreboff, LJ Aronne, NN Ahmad… - … England Journal of …, 2022 - Mass Medical Soc
Background Obesity is a chronic disease that results in substantial global morbidity and
mortality. The efficacy and safety of tirzepatide, a novel glucose-dependent insulinotropic …

Sodium-glucose cotransporter 2 inhibitors and risk of hyperkalemia in people with type 2 diabetes: a meta-analysis of individual participant data from randomized …

BL Neuen, M Oshima, R Agarwal, C Arnott… - Circulation, 2022 - Am Heart Assoc
Background: Hyperkalemia increases risk of cardiac arrhythmias and death and limits the
use of renin-angiotensin-aldosterone system inhibitors and mineralocorticoid receptor …

Association of race/ethnicity, gender, and socioeconomic status with sodium-glucose cotransporter 2 inhibitor use among patients with diabetes in the US

LA Eberly, L Yang, ND Eneanya, U Essien… - JAMA network …, 2021 - jamanetwork.com
Importance Sodium-glucose cotransporter 2 (SGLT2) inhibitors significantly reduce deaths
from cardiovascular conditions, hospitalizations for heart failure, and progression of kidney …

Clinical targets for continuous glucose monitoring data interpretation: recommendations from the international consensus on time in range

T Battelino, T Danne, RM Bergenstal, SA Amiel… - Diabetes …, 2019 - Am Diabetes Assoc
Improvements in sensor accuracy, greater convenience and ease of use, and expanding
reimbursement have led to growing adoption of continuous glucose monitoring (CGM) …

Gestational diabetes: overview with emphasis on medical management

M Lende, A Rijhsinghani - … journal of environmental research and public …, 2020 - mdpi.com
With the rising trend in obesity, the incidence of gestational diabetes mellitus (GDM) and
perinatal complications associated with the condition are also on the rise. Since the early …

[HTML][HTML] Nutrition therapy for adults with diabetes or prediabetes: a consensus report

AB Evert, M Dennison, CD Gardner, WT Garvey… - Diabetes …, 2019 - ncbi.nlm.nih.gov
This Consensus Report is intended to provide clinical professionals with evidencebased
guidance about individualizing nutrition therapy for adults with diabetes or prediabetes …

British Obesity and Metabolic Surgery Society Guidelines on perioperative and postoperative biochemical monitoring and micronutrient replacement for patients …

M O'Kane, HM Parretti, J Pinkney, R Welbourn… - Obesity …, 2020 - Wiley Online Library
Bariatric surgery is recognized as the most clinically and cost‐effective treatment for people
with severe and complex obesity. Many people presenting for surgery have pre‐existing low …

Metformin in 2019

J Flory, K Lipska - Jama, 2019 - jamanetwork.com
Metformin is the first-line pharmacologic treatment for type 2 diabetes and the most
commonly prescribed drug for this condition worldwide, either alone or in combination with …