Uric acid is the end product of purine metabolism in humans. Hyperuricemia is a metabolic
disease caused by the increased formation or reduced excretion of serum uric acid (SUA) …

Diabetes is a chronic metabolic disease that is increasing in prevalence and causes many
complications. Diabetic cardiomyopathy (DCM) is a complication of diabetes that is …

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a vital transcription factor and its induction
is of significant importance for protecting against oxidative damage. Increased levels of …

Even in the absence of coronary artery disease and hypertension, diabetes mellitus (DM)
may increase the risk for heart failure development. This risk evolves from functional and …

The production of free radicals is inevitably associated with metabolism and other enzymatic
processes. Under physiological conditions, however, free radicals are effectively eliminated …

Association of diabetes with an elevated risk of cardiac failure has been clinically evident.
Diabetes potentiates diastolic and systolic cardiac failure following the myocardial infarction …

The prevalence of cardiomyopathy is higher in diabetic patients than those without diabetes.
Diabetic cardiomyopathy (DCM) is defined as a clinical condition of abnormal myocardial …

As a serious cardiovascular complication, diabetic cardiomyopathy (DCM) refers to diabetes‐
related changes in myocardial structure and function, which is obviously different from those …

SARS-CoV-2 by the direct cytopathic effect or indirectly through the propagation of pro-
inflammatory cytokines could cause endothelial dysfunction (ED) and oxidative stress (OS) …

Diabetic cardiomyopathy (DCM) is a common complication in patients with diabetes, and
ultimately leads to heart failure. Endoplasmic reticulum stress (ERS) induced by abnormal …