Targeting CB2R in astrocytes for Parkinson's disease therapy: unraveling the Foxg1-mediated neuroprotective mechanism through autophagy-mediated NLRP3 …

H Zhu, F Xiao, Y Xiao, Y Guo, X Shan, Z Zhang… - Journal of …, 2023 - Springer
Background Inflammasomes in astrocytes have been shown to play a crucial role in the
pathogenesis of neurodegenerative diseases such as Parkinson's disease (PD) and …

ABCD1 transporter deficiency results in altered cholesterol homeostasis

A Buda, S Forss-Petter, R Hua, Y Jaspers, M Lassnig… - Biomolecules, 2023 - mdpi.com
X-linked adrenoleukodystrophy (X-ALD), the most common peroxisomal disorder, is caused
by mutations in the peroxisomal transporter ABCD1, resulting in the accumulation of very …

Ataxia with giant axonopathy in Acbd5-deficient mice halted by adeno-associated virus gene therapy

L Granadeiro, VE Zarralanga, R Rosa, F Franquinho… - Brain, 2024 - academic.oup.com
Acyl-CoA binding domain containing 5 (ACBD5) is a critical player in handling very long
chain fatty acids (VLCFA) en route for peroxisomal β-oxidation. Mutations in ACBD5 lead to …

[PDF][PDF] Pathophysiology of X-Linked Adrenoleukodystrophy: Updates on Molecular Mechanisms

P Parasar, N Kaur, J Singh - Journal of Biotechnology and …, 2024 - fortuneonline.org
X-ALD, an inherited monogenic metabolic disorder affecting the CNS and adrenal white
matter, is caused by mutations in ABCD1 gene leading to defective fatty acid oxidation in the …

Precision Phytochemicals for COVID-19-Induced Olfactory Dysfunction

S Koyama, VDC Shields, T Heinbockel - Bioactive Compounds Against … - taylorfrancis.com
One of the unique symptoms caused by coronavirus disease 2019 (COVID-19) is
chemosensory dysfunction in the senses of smell and taste. Symptoms of chemosensory …