Quantitation of cytomegalovirus: methodologic aspects and clinical applications

M Boeckh, G Boivin - Clinical microbiology reviews, 1998 - Am Soc Microbiol
Cytomegalovirus (CMV) is an important pathogen in transplant recipients and human
immunodeficiency virus (HIV)-infected individuals. Major progress has been made in …

Resistance of herpesviruses to antiviral drugs: clinical impacts and molecular mechanisms

C Gilbert, J Bestman-Smith, G Boivin - Drug resistance updates, 2002 - Elsevier
Nucleoside analogues such as acyclovir and ganciclovir have been the mainstay of therapy
for alphaherpesviruses (herpes simplex virus (HSV) and varicella-zoster virus (VZV)) and …

Drug-resistant human cytomegalovirus infection in children after allogeneic stem cell transplantation may have different clinical outcomes

T Eckle, L Prix, G Jahn, T Klingebiel… - Blood, The Journal …, 2000 - ashpublications.org
Three seropositive pediatric recipients of allogeneic stem cell transplantation out of a group
of 42 patients receiving T-cell–depleted, unrelated transplants and 37 patients receiving T …

Detection of adenovirus using PCR and molecular beacon

SK Poddar - Journal of Virological Methods, 1999 - Elsevier
The polymerase chain reaction (PCR) and a molecular beacon probe were used for the
detection of Adenovirus. A 307 bp DNA fragment from a conserved region of the hexon gene …

The impact of ganciclovir-resistant cytomegalovirus infection after lung transplantation

RM Kruger, WD Shannon, MQ Arens, JP Lynch… - …, 1999 - journals.lww.com
Background. Cytomegalovirus (CMV) resistance to ganciclovir has become increasingly
common in acquired immu; nodeficiency syndrome patients but has only rarely been …

Recombinant phenotyping of cytomegalovirus UL54 mutations that emerged during cell passages in the presence of either ganciclovir or foscarnet

C Gilbert, A Azzi, N Goyette, SX Lin… - Antimicrobial agents and …, 2011 - Am Soc Microbiol
Selection of human cytomegalovirus variants in the presence of ganciclovir or foscarnet led
to 18 DNA polymerase mutations, 14 of which had not been previously studied. Using …

Human cytomegalovirus resistance to antiviral drugs: diagnosis, monitoring and clinical impact

F Baldanti, G Gerna - Journal of Antimicrobial Chemotherapy, 2003 - academic.oup.com
The incidence of human cytomegalovirus (HCMV) disease in AIDS patients decreased
dramatically after the introduction, a few years ago, of highly active antiretroviral combination …

Evaluation of the AMPLICOR cytomegalovirus test with specimens from human immunodeficiency virus-infected subjects

G Boivin, J Handfield, E Toma, G Murray… - Journal of Clinical …, 1998 - Am Soc Microbiol
The AMPLICOR cytomegalovirus (CMV) test, a new qualitative assay for the detection of
CMV DNA in plasma, was compared to conventional methods and quantitative PCR (Q …

Comparative evaluation of the cytomegalovirus DNA load in polymorphonuclear leukocytes and plasma of human immunodeficiency virus-infected subjects

G Boivin, J Handfield, E Toma, G Murray… - Journal of Infectious …, 1998 - academic.oup.com
The cytomegalovirus (CMV) DNA load was determined in polymorphonuclear leukocytes
(PMNL) and plasma samples from 106 human immunodeficiency virus-infected subjects at …

Use of the human cytomegalovirus (HCMV) antigenemia assay for diagnosis and monitoring of HCMV infections and detection of antiviral drug resistance in the …

F Baldanti, MG Revello, E Percivalle, G Gerna - Journal of clinical virology, 1998 - Elsevier
Background: Quantification of viral load in blood has proven to be helpful in the follow-up of
disseminated HCMV infections in immunocompromised patients. Objectives:(i) To describe …