This paper proposes a model to characterize the Dissolved Oxygen Dynamics (DO) for the
Bacillus thuringiensis (Bt) δ-endotoxins production process. The objective of this work is to …

Metabolic flux analysis using carbon labeling experiments (CLEs) is an important tool in
metabolic engineering where the intracellular fluxes have to be computed from the …

With the completion of sequencing projects for several parasite genomes, efforts are
ongoing to make sense of this mass of information in terms of the gene products encoded …

Motivation: Supporting the evolutionary modeling process of dynamic biochemical networks
based on sampled in vivo data requires more than just simulation. In the course of the …

Modeling the transient behavior of continuous culture is of primary importance for the scale‐
up of biological processes. Spatial heterogeneities increase with the reactor size and micro …

A novel methodology is established to convert a set of elementary chemical reactions into
topologically-equivalent electrical circuits. The circuit analog is then simulated to elucidate …

A systems approach to biology requires a principled approach to pathway identification. In
this study, the two nuclear petite yeast mutants K1Δpet191a and K1Δpet191ab and their …

Strain improvement and fermentation optimization are two fundamental tasks in industrial
fermentation. Multi‐scale study on the optimization of industrial fermentation has been …

(57) ABSTRACT A method for intracellular metabolic flux analysis comprising (a) culturing
cells in a medium not containing any isotope labeled substrate to a target phase of the …

Polyhydroxyalkanoates (PHAs) are natural polyesters that accumulate in numerous
microorganisms as a carbon-and energy-storage material under the nutrient-limiting …