Macrophages in inflammation, repair and regeneration
Tissue injury triggers a complex series of cellular responses, starting from inflammation
activated by tissue and cell damage and proceeding to healing. By clearing cell debris …
activated by tissue and cell damage and proceeding to healing. By clearing cell debris …
[HTML][HTML] Zinc-finger proteins in health and disease
M Cassandri, A Smirnov, F Novelli, C Pitolli… - Cell death …, 2017 - nature.com
Zinc-finger proteins (ZNFs) are one of the most abundant groups of proteins and have a
wide range of molecular functions. Given the wide variety of zinc-finger domains, ZNFs are …
wide range of molecular functions. Given the wide variety of zinc-finger domains, ZNFs are …
[HTML][HTML] Opposing gene regulatory programs governing myofiber development and maturation revealed at single nucleus resolution
Skeletal muscle fibers express distinct gene programs during development and maturation,
but the underlying gene regulatory networks that confer stage-specific myofiber properties …
but the underlying gene regulatory networks that confer stage-specific myofiber properties …
[HTML][HTML] Regulation and phylogeny of skeletal muscle regeneration
MB Baghdadi, S Tajbakhsh - Developmental biology, 2018 - Elsevier
One of the most fascinating questions in regenerative biology is why some animals can
regenerate injured structures while others cannot. Skeletal muscle has a remarkable …
regenerate injured structures while others cannot. Skeletal muscle has a remarkable …
[HTML][HTML] Skeletal muscle regeneration in cardiotoxin-induced muscle injury models
Y Wang, J Lu, Y Liu - International journal of molecular sciences, 2022 - mdpi.com
Skeletal muscle injuries occur frequently in daily life and exercise. Understanding the
mechanisms of regeneration is critical for accelerating the repair and regeneration of …
mechanisms of regeneration is critical for accelerating the repair and regeneration of …
[HTML][HTML] Factors regulating or regulated by myogenic regulatory factors in skeletal muscle stem cells
T Shirakawa, T Toyono, A Inoue, T Matsubara… - Cells, 2022 - mdpi.com
MyoD, Myf5, myogenin, and MRF4 (also known as Myf6 or herculin) are myogenic
regulatory factors (MRFs). MRFs are regarded as master transcription factors that are …
regulatory factors (MRFs). MRFs are regarded as master transcription factors that are …
Mef2 and the skeletal muscle differentiation program
MV Taylor, SM Hughes - Seminars in cell & developmental biology, 2017 - Elsevier
Mef2 is a conserved and significant transcription factor in the control of muscle gene
expression. In cell culture Mef2 synergises with MyoD-family members in the activation of …
expression. In cell culture Mef2 synergises with MyoD-family members in the activation of …
Krüppel-like factors family regulation of adipogenic markers genes in bovine cattle adipogenesis
Intramuscular fat (IMF) content is a crucial determinant of meat quality traits in livestock. A
network of transcription factors act in concert to regulate adipocyte formation and …
network of transcription factors act in concert to regulate adipocyte formation and …
scEpath: energy landscape-based inference of transition probabilities and cellular trajectories from single-cell transcriptomic data
Motivation Single-cell RNA-sequencing (scRNA-seq) offers unprecedented resolution for
studying cellular decision-making processes. Robust inference of cell state transition paths …
studying cellular decision-making processes. Robust inference of cell state transition paths …
A TGF-β/KLF10 signaling axis regulates atrophy-associated genes to induce muscle wasting in pancreatic cancer
A Dasgupta, DF Gibbard, RE Schmitt… - Proceedings of the …, 2023 - National Acad Sciences
Cancer cachexia, and its associated complications, represent a large and currently
untreatable roadblock to effective cancer management. Many potential therapies have been …
untreatable roadblock to effective cancer management. Many potential therapies have been …